Abstract The transformation biology of secondary acute myeloid leukaemia (AML) from myelodysplastic syndromes (MDSs) is still not fully understood. We performed paired self‐controlled sequencing, including targeted, whole exome, and single‐cell RNA sequencing, in a cohort of MDS patients to search for AML transformation‐related mutations (TRMs). Thirty‐
Feng Xu+5 more
wiley +1 more source
Direct evidence for new T-cell generation by patients after either T-cell–depleted or unmodified allogeneic hematopoietic stem cell transplantations [PDF]
Sharon R. Lewin+10 more
openalex +1 more source
Preemptive cellular immunotherapy after T-cell-depleted allogeneic hematopoietic stem cell transplantation [PDF]
Frédéric Baron, Y Beguin
openalex +1 more source
Donor mesenchymal stem cells trigger chronic graft-versus-host disease following minor antigen-mismatched bone marrow transplantation [PDF]
Chronic graft-versus-host disease (cGVHD) is a complication after minor antigen mismatched bone marrow transplantation (BMT) characterized by an autoimmune-type reaction in various organs.
Hideyuki Okano+12 more
core +1 more source
Implementation of an AI-based MRD evaluation and prediction model for multiple myeloma [PDF]
With the application of hematopoietic stem cell transplantation and new drugs, the progression-free survival rate and overall survival rate of multiple myeloma have been greatly improved, but it is still considered as a kind of disease that cannot be completely cured.
arxiv
Increased presence of anti-HLA antibodies early after allogeneic granulocyte colony-stimulating factor-mobilized peripheral blood hematopoietic stem cell transplantation compared with bone marrow transplantation [PDF]
V. Lapierre
openalex +1 more source
The role of the host—Neutrophil biology
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple+4 more
wiley +1 more source
Purified Allogeneic Hematopoietic Stem Cell Transplantation Blocks Diabetes Pathogenesis in NOD Mice [PDF]
Georg F. Beilhack+7 more
openalex +1 more source
Allogeneic Hematopoietic Stem Cell Transplantation in the Active Duty Military Population: 1987–2001 [PDF]
Brenda Frye+6 more
openalex +2 more sources