Results 81 to 90 of about 11,297 (212)

Neonatal alloimmune thrombocytopenia

BMJ, 2003
Neonatal alloimmune thrombocytopenia—caused by movement of maternal alloantibodies directed against fetal platelet antigens across the placenta—is the most common cause of severe neonatal thrombocytopenia.1 These alloantibodies cause thrombocytopenia, which may result in intracranial haemorrhage.2 3 Most cases arise unexpectedly, and prompt diagnosis ...
H Yarranton, David L. Allen, J Birchall, R Rayment, J Hewertson, Michael F. Murphy, David J. Roberts   +6 more
openaire   +4 more sources

Systemic Inflammatory Diseases in Children With Sickle Cell Disease: A French Multicenter Observational Study on Diagnostic and Therapeutic Issues

Pediatric Blood &Cancer, Volume 72, Issue 4, April 2025.
ABSTRACT Background Systemic inflammatory diseases (SIDs) have been reported in patients with sickle cell disease (SCD), but clinical data in children are scarce. Objectives To identify clinical and laboratory features at diagnosis of SID in children with SCD and to describe their evolution.
Caroline Vinit, Corinne Guitton, Mariane De Montalembert, Patricia Benhaim, Lahoueri Amor‐Chelihi, Brigitte Bader‐Meunier, Florence Missud, Isabelle Melki, Vincent Gajdos, Cécile Arnaud, Annie Kamden, Oussama Charara, Véronique Hentgen, Sylvie Nathanson, Coralie Bloch, Ulrich Meinzer, Pierre Quartier, Isabelle Kone‐Paut, Loïc De Pontual, Luu‐Ly Pham   +19 more
wiley   +1 more source

Transfusing selected RhD negative patients with RhD positive packed red cell concentrates resulted in lower frequency of anti‐D development and saved almost two thousand RhD negative concentrates during 5 years

Transfusion Medicine, Volume 35, Issue 2, Page 138-143, April 2025.
Abstract Background The Blood Bank at Oslo University Hospital implements restrictions when the stocks of blood groups O and A RhD negative packed red blood cell concentrates (PRBCCs) drop below 60 units due to high demand and low donor availability. Restrictions entail transfusing RhD negative male patients and women >50 years with RhD positive units,
Inger Margit Alm, Elin Brenna, Çiğdem Akalın Akkök   +2 more
wiley   +1 more source

Study of Frequency and Characteristics of Red Blood Cell Alloimmunization in Thalassemic Patients: Multicenter Study from Palestine [PDF]

, 2019
Background. - alassemia is a common inherited hemolytic disorder in Palestine. Red blood cell (RBC) transfusion is the principal treatment but it may cause RBC alloimmunization. is study was conducted to determine the prevalence and characteristics of
Abu Seir, Rania, Abu Taha, Adham, Abu Zenah, Omar, Ali, Hammam, Suleiman, Sa’d, Yaseen, Ahmad, Younis, Khaled   +6 more
core  

Transfusion‐Related Acute Lung Injury: from Mechanistic Insights to Therapeutic Strategies

Advanced Science, Volume 12, Issue 11, March 20, 2025.
This review systematically presents an updated and comprehensive overview of transfusion‐related acute lung injury (TRALI), a serious complication of blood transfusions. It explores TRALI's clinical features, potential causes, and immune mechanisms. Key insights include the roles of signaling pathways and possible therapies, with a focus on prevention ...
Xiaobin Fang, Chunheng Mo, Ling Zheng, Fei Gao, Fu‐Shan Xue, Xiaochun Zheng   +5 more
wiley   +1 more source

Plasmapheresis for the Treatment of Anti-M Alloimmunization in Pregnancy

Case Reports in Obstetrics and Gynecology, 2020
Intrauterine transfusion is the standard antenatal treatment for a fetus with severe anemia. Plasmapheresis is an alternative treatment for cases with a history of severe hemolytic disease of the fetus and newborns at less than 20 weeks of gestation ...
Yohei Maki, J. Ushijima, S. Furukawa, H. Inagaki, H. Takenouchi, S. Fujimoto, H. Sameshima   +6 more
semanticscholar   +1 more source

Selecting patients with sickle cell disease for gene addition or gene editing‐based therapeutic approaches: Report on behalf of a joint EHA Specialized Working Group and EBMT Hemoglobinopathies Working Party consensus conference

HemaSphere, Volume 9, Issue 3, March 2025.
ABSTRACT Sickle cell disease (SCD) remains associated with reduced life expectancy and poor quality of life despite improvements observed in the last decades mostly related to comprehensive care, use of hydroxycarbamide, screening to identify patients at risk of strokes, and implementation of safe transfusion protocols.
Lucia de Franceschi, Franco Locatelli, David Rees, Christian Chabannon, Jean‐Hugues Dalle, Stefano Rivella, Achille Iolascon, Stephan Lobitz, Miguel R. Abboud, Josu de la Fuente, Pagona Flevari, Emanuele Angelucci, Mariane de Montalembert   +12 more
wiley   +1 more source

Preoperative anemia management [PDF]

, 2018
This article answers the question: My patient's blood type is O negative, but the platelet transfusion he received yesterday was Rh positive. What is the risk of developing an anti-D alloantibody after exposure to an Rh positive platelet unit, and does ...
Coberly, Emily
core   +1 more source

Anti-E Alloimmunization: A Rare Cause of Severe Fetal Hemolytic Disease Resulting in Pregnancy Loss [PDF]

, 2009
We report a case of severe intrauterine hemolysis caused by sole anti-E alloimmunization. A 36-year-old multipara woman presented with hydrops fetalis at 27 weeks of gestation. She had a history of previous neonatal death.
An-shine Chao, Angel Chao, Article Id, Reyin Lien, See-yin Ho, Yao-lung Chang   +5 more
core   +4 more sources

Rhesus (Rh) alloimmunization [PDF]

, 2008
This issue of eMedRef provides information to clinicians on the pathophysiology, diagnosis, and therapeutics of Rhesus (Rh ...
Taraday, Julie
core