Results 251 to 260 of about 12,622 (280)

Peripartum allopregnanolone blood concentrations and depressive symptoms: a systematic review and individual participant data meta-analysis. [PDF]

Mol Psychiatry
Schoretsanitis G, Osborne LM, Sundström-Poromaa I, Wenzel ES, Payne JL, Barbui C, Gastaldon C, Deligiannidis KM.   +7 more
europepmc   +1 more source

Different levels of Allopregnanolone in girls with precocious pubarche and central precociuos puberty

, 2003
Barbara Predieri, Lorenzo Iughetti, L. Cobellis, Stefano Luisi, Elena Casarosa, Felice Petraglia, Sergio Bernasconi   +6 more
openalex   +1 more source

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Role of PPAR-allopregnanolone signaling in behavioral and inflammatory gut-brain axis communications.

Biological Psychiatry, 2023
The gut microbiome regulates emotional behavior, stress responses, and inflammatory processes by communicating with the brain. How and which neurobiological mediators underlie this communication remain poorly understood. Peroxisome proliferator-activated
G. Pinna
semanticscholar   +1 more source

Allopregnanolone and mood disorders

Progress in Neurobiology, 2014
Certain women experience negative mood symptoms during the menstrual cycle and progesterone addition in estrogen treatments. In women with PMDD increased negative mood symptoms related to allopregnanolone increase during the luteal phase of ovulatory menstrual cycles. In anovulatory cycles no symptom or sex steroid increase occurs.
T, Bäckström, M, Bixo, M, Johansson, S, Nyberg, L, Ossewaarde, G, Ragagnin, I, Savic, J, Strömberg, E, Timby, F, van Broekhoven, G, van Wingen   +10 more
openaire   +3 more sources

Regenerative potential of allopregnanolone

Brain Research Reviews, 2008
The neuroendocrine status of the brain has been linked to the quality of the aging process, to the risk of Alzheimer's disease and to progression of neurodegenerative pathology. Data from multiple levels of analysis ranging from in vitro cellular models to in vivo animal models to clinical investigations indicate that the decline of neurosteroids play ...
Jun Ming, Wang, Lifei, Liu, Ronald W, Irwin, Shuhua, Chen, Roberta Diaz, Brinton   +4 more
openaire   +2 more sources

Neurosteroids: 7-aza-allopregnanolone—a poor substitute for allopregnanolone

Tetrahedron, 2007
7-Nor-20-oxopregn-5-en-3β-yl acetate was converted into (20R)-5β,6β-epoxy-7-nor-5β-pregnane-3β,20-diyl diacetate in three steps. Stereospecific migration of the 6α-hydride ion led to a 6-oxo derivative with a 5α-configuration. The (Z)-oxime of this ketone underwent Beckmann rearrangement to yield a lactam with the nitrogen in position 7.
Alexander Kasal, Zdena Krištofíková, Miloš Buděšínský   +2 more
openaire   +1 more source

A novel radioimmunoassay of allopregnanolone

Steroids, 1995
A radioimmunoassay for determination of 3 alpha-hydroxy-5 alpha-pregnan-20-one (allopregnanolone) in serum or plasma has been developed and evaluated. The method employs rabbit antiserum to 3 alpha-hydroxy-5 alpha-pregnane-11,20-dione-11-O-carboxymethyloxime bovine serum-albumin conjugate and tritiated radioligand.
M, Bicíková, O, Lapcík, R, Hampl, L, Stárka, R, Knuppen, O, Haupt, L, Dibbelt   +6 more
openaire   +2 more sources

Allopregnanolone in Women with Premenstrual Syndrome

Hormone and Metabolic Research, 1998
5Alpha-reduced metabolites of progesterone, especially 3alpha-hydroxy-5alpha-pregnan-20-one (allopregnanolone) are now listed to neurosteroids. Their anesthetic properties can be explained by their allosteric interaction with GABA(A) receptors. A woman's organism is provided with an abundance of progesterone during the luteal phase of the menstrual ...
M, Bicíková, L, Dibbelt, M, Hill, R, Hampl, L, Stárka   +4 more
openaire   +2 more sources