Results 111 to 120 of about 1,971,711 (246)

Enzymatic Mpemba Effect: Slowing of biochemical reactions by increasing enzyme concentration [PDF]

open access: yesarXiv
Increasing the enzyme concentration generally speeds up enzymatic reactions. However, in this Letter, we show that increasing the enzyme concentration can also slow down the enzymatic reaction. We consider a simple allosteric protein with multiple modification sites, catalyzed by two enzymes with the same catalytic activity, but slightly different ...
arxiv  

Disorder driven allosteric control of protein activity

open access: yesCurrent Research in Structural Biology, 2020
Studies of protein allostery increasingly reveal an involvement of the back and forth order-disorder transitions in this mechanism of protein activity regulation.
Wei-Ven Tee   +2 more
doaj  

Prediction and confirmation of a switch-like region within the N-terminal domain of hSIRT1

open access: yesBiochemistry and Biophysics Reports, 2022
Many proteins display conformational changes resulting from allosteric regulation. Often only a few residues are crucial in conveying these structural and functional allosteric changes.
Angelina T. Huynh   +10 more
doaj  

Bypass mechanism of F$_1$-ATPase for asymmetric enzyme kinetics [PDF]

open access: yesarXiv
We discovered novel enzyme kinetics of F$_1$-ATPase, a biomolecular motor that synthesizes and hydrolyzes adenosine triphosphate (ATP), using single-molecule experiments and numerical simulations. The enzyme kinetics of F$_1$-ATPase followed the Michaelis-Menten equation in ATP hydrolysis but deviated from it in ATP synthesis, indicating asymmetric ...
arxiv  

Mechanism of antifreeze proteins action, based on Hierarchic theory of water and new ''clusterphilic'' interaction [PDF]

open access: yesarXiv, 2001
A basically new Hierarchic theory, general for solids and liquids (Kaivarainen, 2001, 2000, 1995, 1992), has been briefly described and illustrated by computer simulations on examples of water and ice. Full description of theory and its numerous applications are presented in series of articles at the arXiv of Los-Alamos (see http://arXiv.org/abs ...
arxiv  

Author Correction: The endocannabinoid hydrolase FAAH is an allosteric enzyme. [PDF]

open access: yesSci Rep, 2020
Dainese E   +9 more
europepmc   +1 more source

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