Results 141 to 150 of about 57,293 (304)

Allosteric regulation of lysosomal enzyme recognition by the cation-independent mannose 6-phosphate receptor [PDF]

, 2020
Linda J. Olson, Sandeep K. Misra, Mayumi Ishihara, K.P. Battaile, Oliver C. Grant, Amika Sood, Robert J. Woods, Jung‐Ja P. Kim, Michael Tiemeyer, Gang Ren, Joshua S. Sharp, Nancy Dahms   +11 more
openalex   +1 more source

Pharmacological Inhibition of APT2 by Solasonine Promotes Ferroptosis Through Palmitoylation Modulation in Gallbladder Cancer

Phytotherapy Research, EarlyView.
Schematic illustration of SS‐induced ferroptosis through targeting APT2‐mediated STAT3 palmitoylation in GBC cells. ABSTRACT Gallbladder cancer (GBC), the most prevalent and lethal biliary tract malignancy, lacks effective therapeutic strategies. Solasonine (SS), a bioactive steroidal alkaloid derived from Solanum nigrum L, exhibits antitumor activity ...
Liu‐qing Shi, Jing‐wei Zhao, Jia‐yun Zhu, Cheng Zhao, Zi‐yi Yang, Li‐jia Pan, Ben Ma, Zheng‐yu Chen, Zi‐ying Wang, Chun‐jie Li, Shi‐lei Liu, Jia‐wei Mei, Ping Dong   +12 more
wiley   +1 more source

Method for the controlled induction of metabolic collapse by increasing the apparent Km value of an allosteric enzyme

Fadel, Yassin
openalex   +2 more sources

Development of novel active site and allosteric inhibitors of enzymes associated with cancer, neurodegenerative diseases and bacterial infections

, 2013
Lisa Pirrie
openalex   +1 more source

Chorismate Mutase/Prephenate Dehydratase from Escherichia coli K12. Effects of Chemical Modification on the Enzymic Activities and Allosteric Inhibition [PDF]

, 1977
M J Gething, B E Davidson
openalex   +1 more source

Flexoelectric Polarization‐Enhanced Gd‐Based Nanoflowers for Efficient Phosphatase‐Mimicking Dephosphorylation

Small Structures, EarlyView.
Flexoelectric polarization is harnessed to dynamically enhance phosphatase‐mimicking catalysis in Gd‐based nanoflowers, enabling ultrasound‐responsive and efficient biophosphate ester hydrolysis through strain‐induced electronic modulation. Phosphatase‐mimicking nanozymes provide highly stable enzyme‐like activity but remain limited by their static ...
Linjing Su, Jingyan Xu, Rong Huang, Jinlan Liao, Lixue Zhao, Ling Li, Zhi Zhang, Yuhao Xiong   +7 more
wiley   +1 more source

Luteinizing hormone receptor knockout mouse: What has it taught us?

Andrology, EarlyView.
Abstract Luteinizing hormone (LH), along with its agonist choriongonadotropin (hCG) in humans, is the key hormone responsible for the tropic regulation of the gonadal function. LH and hCG act through their cognate receptor, the luteinizing hormone/choriongonadotropin receptor (LHCGR; more appropriately LHR in rodents lacking CG), located in the testis ...
Ilpo T. Huhtaniemi
wiley   +1 more source

Folding, misfolding, and regulation of intracellular traffic of G protein‐coupled receptors involved in the hypothalamic–pituitary–gonadal axis

Andrology, EarlyView.
Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre, Ross C. Anderson, Teresa Zariñán, Rubén Gutiérrez‐Sagal, Eduardo Jardón‐Valadez, Claire L. Newton   +5 more
wiley   +1 more source

Evaluating the limitations of Bayesian metabolic control analysis. [PDF]

PLoS Comput Biol
Shin J, Carothers JM, Sauro HM.
europepmc   +1 more source

Cyclic AmplifiedProgrammable Allosteric DNA Biosensorfor Enzyme-Triggered Spatially Controlled Mitochondrial MolecularImaging

Jingzhe Zang (22007029), Tingting Wang (123983), Fei Zhang (85787), Lifeng Li (3289017), Zhidan Yu (13740879), Meng Sun (124749), Kangbo Liu (495128), Xianwei Zhang (1917706), Peng Wang (34436), Wancun Zhang (1708051)   +9 more
openalex   +1 more source