A Comparative Analysis of Michaelis-Menten, Hill, and Allosteric Models in Drug Metabolism
Iraqi Journal of Industrial ResearchBackground: Enzyme Kinetics it is a fundamental part of metabolic biochemistry because it helps to explore the mechanism of action and interaction of all substrates under the influence as well as environmental factors.
Ziyad K. Radeef
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Studies on medium-chain fatty acyl-coenzyme A synthetase. Enzyme fraction I: mechanism of reaction and allosteric properties [PDF]
, 1968 Jacob Bar‐Tana, G. Rose
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Angewandte Chemie International Edition, Accepted Article.This review explores the potential of mechanochemistry in the late‐stage modification of active pharmaceutical ingredients (APIs), offering a comprehensive analysis of methods designed to transform structurally complex molecular scaffolds. By examining the scope, efficiency, and mechanistic aspects of these approaches, the review highlights protocols ...
Johanna Templ, Lars Borchardt
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Reversible adsorption of enzymes as a possible allosteric control mechanism [PDF]
, 1969 C.J. Masters +3 more
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Analysis of kinetic data of allosteric enzymes by a linear plot [PDF]
, 1969 A Horn, H Börnig
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Hepatic gluconeogenesis and regulatory mechanisms in lactating ruminants: A literature review
Animal Research and One Health, EarlyView.phosphoenolpyruvate carboxy kinase, FBP1, and glucose‐6‐phosphatase are key rate‐limiting enzymes that determine the efficiency of gluconeogenesis. The main substrate for gluconeogenesis in the liver of ruminants is propionate, which provides more than 60% of the carbon source for gluconeogenesis.
Guoyan Wang +5 more
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Arthritis &Rheumatology, EarlyView.Objective Podocytes are integral to the maintenance of the glomerular filtration barrier. Their injury results in proteinuria and disease progression in lupus nephritis (LN). Aberrant IgG glycosylation drives podocyte injury in LN and leads to cytoskeletal rearrangement, motility changes, and decreased nephrin production.
Rhea Bhargava +9 more
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Disorder driven allosteric control of protein activity
Current Research in Structural Biology, 2020 Studies of protein allostery increasingly reveal an involvement of the back and forth order-disorder transitions in this mechanism of protein activity regulation.
Wei-Ven Tee +2 more
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The allosteric mechanism of bovine liver glutamate dehydrogenase. Evidence from circular-dichroism studies for a conformational change in the ternary complex enzyme-(oxidized nicotinamide-adenine dinucleotide)-glutarate [PDF]
, 1977 S S Chen, Paul C. Engel, Peter M. Bayley
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Metal‐Mediated Protein Engineering within Live Cells
Chemistry – An Asian Journal, Volume 20, Issue 6, March 17, 2025.This review discusses how metal ions can mediate protein modification within live cells. With its easy handling, rapid solubility, and ease of internalization within the cells, metal ions can be an excellent stimulus for many organic reactions needed within an intracellular medium, which can modify proteins and lead to applications in chemistry ...
Pritam Ghosh
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