Structural mechanisms of allosteric regulation in the human cis-prenyltransferase complex. [PDF]
Giladi M +8 more
europepmc +1 more source
Allosteric Inhibitors of the Enzyme IspD of the Non-Mevalonate Pathway for Isoprenoid Biosynthesis
Anatol Schwab
openalex +2 more sources
The rice receptor‐like pseudokinase LENG enhances chilling tolerance by binding to and suppressing the kinase activity of OsCRPK1, thereby preventing OsCRPK1‐mediated phosphorylation of the cold‐tolerance positive regulator OsGF14d. ABSTRACT Cold damage during the seedling and reproductive stages has a pronounced impact on rice development and yield ...
Shuting Yuan +12 more
wiley +1 more source
Endocannabinoid oxygenation by prostaglandin H synthase-2: Chemistry and biology. [PDF]
Rouzer CA, Marnett LJ.
europepmc +1 more source
Shortest Path Map correlation-based tool for capturing functionally relevant allosteric networks and its application in enzyme design [PDF]
Esther Pruna Cortada, Sílvia Osuna
openalex +1 more source
A novel single‐cell NAD‐ME C4 subtype integrated with CAM and bicarbonate use in an aquatic plant
Summary Many plants maximize photosynthesis by using a CO2‐concentrating mechanism (CCM). Based on physiology, the freshwater plant Ottelia alismoides has three CCMs: C4 metabolism (NAD‐malic enzyme (NAD‐ME) subtype) and bicarbonate‐use during the day plus crassulacean acid metabolism (CAM) at night and lacks Kranz anatomy. Here, we combined a range of
Hong Sheng Jiang +11 more
wiley +1 more source
GTP cycling protein (GCP): An ancient player for allosteric gatekeeping. [PDF]
Liu JL.
europepmc +1 more source
USP10 in Neurological Disorders: Mechanistic Insights and Emerging Therapeutic Strategies
USP10 is a deubiquitinating enzyme that affects neurological diseases through multiple mechanisms, including the accumulation of toxic proteins, autophagy, and immune responses. In this review, we discuss the structure and characteristics of USP10 and summarize the role of USP10 in neurological disorders.
Celemuge +5 more
wiley +1 more source
Support Vector Machine Identification of Small Molecule Binders to an Understudied Allosteric Site of SARS-CoV-2 Mpro for Next-Generation PROTAC-Based Therapeutics. [PDF]
Fassi EMA +7 more
europepmc +1 more source

