Allosteric regulation of L-lactate dehydrogenase: Beyond effector-mediated tetramerization. [PDF]
Cai H+5 more
europepmc +1 more source
The tested Phlomis species are a rich source of bioactive molecules with potential therapeutic applications, and selecting appropriate extraction solvents is crucial for achieving the targeted biological activity. Phlomis species (family Lamiaceae) are highly valued as food and herbal medicine.
Sakina Yagi+8 more
wiley +1 more source
Old player, new roles: defining the role of the plastidial phosphorylase. [PDF]
Seung D, Orzechowski S, Fettke J.
europepmc +1 more source
Allosteric Regulation of Protein Kinase Enzymes via an Electrostatic Switch that Modulates Active Site Dynamics [PDF]
Matthew A. Young+2 more
openalex +1 more source
A library of easily synthesizable CAPE analogs was screened in silico against the dengue virus envelope protein. Compound LQM778 showed stable binding and promising inhibitory potential. This study highlights LQM778 as a candidate for future in vitro validation and structural optimization toward accessible antiviral agents against dengue.
Luis Alfonso Cárdenas‐Granados+9 more
wiley +1 more source
Zinc enhancement of cytidine deaminase activity highlights a potential allosteric role of loop-3 in regulating APOBEC3 enzymes [PDF]
Ailie Marx, Meytal Galilee, Akram Alian
openalex +1 more source
Quantifying Dynamic Regulation in Metabolic Pathways with Nonparametric Flux Inference [PDF]
He, Fei, Stumpf, Michael P H
core +1 more source
Dark‐operative protochlorophyllide oxidoreductase (DPOR) participates in photosynthesis by catalyzing the ATP‐dependent reduction of protochlorophyllide to chlorophyllide. Structurally and mechanistically resembling nitrogenase, DPOR′s mechanism was investigated using visible spectroscopy.
Giada Bedendi+2 more
wiley +1 more source
Structural and dynamics studies of human phenylalanine hydroxylase, a highly regulated allosteric enzyme [PDF]
Marte I. Flydal+6 more
openalex +1 more source
B-factor analysis suggests that
S. Saran, D.A.R. Sanders
openalex +1 more source