Results 291 to 300 of about 22,949 (304)

An orally bioavailable positive allosteric modulator of the mGlu4 receptor with efficacy in an animal model of motor dysfunction

Bioorganic and Medicinal Chemistry Letters, 2010
Stephen P East, Christian Eickmeier, Boris Ferger   +2 more
exaly  

Preclinical profile of a novel metabotropic glutamate receptor 5 positive allosteric modulator

European Journal of Pharmacology, 2011
Jeffrey S Smith, Patricia Schroeder, Minli Zhang   +2 more
exaly  

Allosteric Modulators

2015
openaire   +1 more source

Functional properties and mechanism of action of PPTQ, an allosteric agonist and low nanomolar positive allosteric modulator at GABAA receptors

Biochemical Pharmacology, 2018
Nawid Madjroh, Christoffer Bundgaard, Anders A Jensen   +2 more
exaly  

Allosteric Modulators

2008
openaire   +1 more source

AlloFinder: a strategy for allosteric modulator discovery and allosterome analyses

Nucleic Acids Research, 2018
Shaoyong Lu, Qiancheng Shen, Renxiao Wang   +2 more
exaly  

Anxiolytic-like effects of PHCCC, an allosteric modulator of mGlu4 receptors, in rats

European Journal of Pharmacology, 2004
Katarzyna Stachowicz, Aleksandra Kłodzińska, E Chojnacka-Wójcik   +2 more
exaly  

MK-7622: A First-in-Class M1 Positive Allosteric Modulator Development Candidate

ACS Medicinal Chemistry Letters, 2018
Douglas C Beshore, Christina N Di Marco, Marion Wittmann   +2 more
exaly  

Effect of the Novel Positive Allosteric Modulator of Metabotropic Glutamate Receptor 2 AZD8529 on Incubation of Methamphetamine Craving After Prolonged Voluntary Abstinence in a Rat Model

Biological Psychiatry, 2015
Daniele Caprioli, Marco Venniro, Xuan Li   +2 more
exaly  

Discovery of VU0409106: A negative allosteric modulator of mGlu5 with activity in a mouse model of anxiety

Bioorganic and Medicinal Chemistry Letters, 2013
Andrew S Felts, Ryan D Morrison, Daryl F Venable   +2 more
exaly