Results 91 to 100 of about 63,430 (242)

Efficacy and safety of a selective partial agonist for nociception/orphanin‐FQ peptide (NOP) receptors in patients with insomnia disorder

British Journal of Clinical Pharmacology, EarlyView.
Aims Insomnia is a common sleep disorder, affecting up to 20% of the world population and adversely impacting productivity, health, and overall well‐being. Although pharmacologic options exist to treat insomnia, the health‐related quality of life for patients who are prescribed hypnotics is no higher than for those who are not, revealing a significant ...
Garth T. Whiteside, Ellie He, S. Shet Manjunath, Mingyan Zhou, Maha Ahmad, Stephen C. Harris   +5 more
wiley   +1 more source

Full-length nuclear receptor allosteric regulation. [PDF]

J Lipid Res, 2023
Choi WJ, Haratipour Z, Blind RD.
europepmc   +1 more source

Identification of Regions of the Tomato γ-Glutamyl Kinase That Are Involved in Allosteric Regulation by Proline [PDF]

, 2003
Tomomichi Fujita, Albino Maggio, Mario G. García-Ríos, Cynthia V. Stauffacher, Ray A. Bressan, László N. Csonka   +5 more
openalex   +1 more source

Defective Ribosome Recycling: A Bridge Between Translation Fidelity, Organelle Dysfunction, and Diseases

BioEssays, EarlyView.
The Role of Ribosome Recycling in Human Diseases This diagram highlights how disruptions in ribosome translation and recycling can negatively impact cellular and organismal health. Usually, these processes operate efficiently to maintain cellular protein homeostasis.
Foozhan Tahmasebinia, Zhihao Wu
wiley   +1 more source

Allosteric regulation of tRNA import: interactions between tRNA domains at the inner membrane of Leishmania mitochondria [PDF]

, 2003
Srikanta Goswami
openalex   +1 more source

Short‐chain acyl post‐translational modifications in cancers: Mechanisms, roles, and therapeutic implications

Cancer Communications, EarlyView.
Abstract Post‐translational modifications (PTMs) play a pivotal role in epigenetic regulation and are key pathways for modulating protein functionality. PTMs involve the covalent attachment of distinct chemical groups, such as succinyl, crotonyl, and lactyl, at specific protein sites, which alter protein structure, function, stability, and activity ...
Ting Wu, Yingqi Zhao, Xin Zhang, Yuanhe Wang, Qiuchen Chen, Mingrong Zhang, Huan Sheng, Yuying Zhang, Jinyu Guo, Jun Li, Yuxuan Fan, Ziqing Wang, Yalun Li, Haoran Wang, Minjie Wei, Xiaoyun Hu, Huizhe Wu   +16 more
wiley   +1 more source

Allosteric regulation and inhibition of protein kinases. [PDF]

Biochem Soc Trans, 2023
Mingione VR, Paung Y, Outhwaite IR, Seeliger MA.   +3 more
europepmc   +1 more source

Structure and allosteric regulation of the αXβ2 integrin I domain [PDF]

, 2003
Thomas Vorup‐Jensen, Christian Ostermeier, Motomu Shimaoka, Ulrich Hommel, Timothy A. Springer   +4 more
openalex   +1 more source

Periodontitis treatment and microbiome in a patient with FAM20A mutation: Case study of 1.5 years

Clinical Advances in Periodontics, EarlyView.
Abstract Background Enamel‐renal‐gingival syndrome (ERGS) is an autosomal recessive disorder caused by mutations in the FAMily with sequence similarity 20A (FAM20A) gene, and is characterized by amelogenesis imperfecta, delayed or failed tooth eruption, and periodontitis.
John Rong Hao Tay, Preethi Balan, Chaminda Jayampath Seneviratne   +2 more
wiley   +1 more source

Disease-causing cystathionine β-synthase linker mutations impair allosteric regulation. [PDF]

J Biol Chem, 2023
Roman JV, Mascarenhas R, Ceric K, Ballou DP, Banerjee R.   +4 more
europepmc   +1 more source