Results 121 to 130 of about 67,162 (289)

Crystal structure and biochemical properties of putrescine carbamoyltransferase from Enterococcus faecalis: Assembly, active site, and allosteric regulation

, 2012
Dashuang Shi, Xiaolin Yu, Gengxiang Zhao, Jeremy Ho, Shennon Lu, Norma M. Allewell, Mendel Tuchman   +6 more
openalex   +2 more sources

Figure S1 from Kinetic Characterization of ASXL1/2-Mediated Allosteric Regulation of the BAP1 Deubiquitinase

, 2023
Hongzhuang Peng, Joel Cassel, Daniel S. McCracken, Jeremy W. Prokop, Eleonora Sementino, Mitchell Cheung, Paul R. Collop, Alexander Polo, Surbhi Joshi, Jacob P. Mandell, Kasirajan Ayyanathan, David A. Hinds, S. Bruce Malkowicz, J. William Harbour, A. Bowcock, Joseph M. Salvino, Eileen J. Kennedy, Joseph R. Testa, Frank J. Rauscher   +18 more
openalex   +1 more source

Structural basis for the allosteric regulation of the SbtA bicarbonate transporter by the P _II -like protein, SbtB, from Cyanobium sp. PCC7001

, 2019
Joe A. Kaczmarski, Nansook Hong, Bratati Mukherjee, Laura T. Wey, Loraine M. Rourke, Britta Förster, Thomas S. Peat, G. Dean Price, Colin J. Jackson   +8 more
openalex   +1 more source

Biochemistry Learning in Higher Education: A Systematic Review on Methodologies and Teaching Resources

Biochemistry and Molecular Biology Education, EarlyView.
ABSTRACT The teaching of biochemistry in higher education presents several challenges, including the complexity of molecular visualization, the use of technical terminology, and the vast amount of content covered in courses. This systematic review explores current research on biochemistry teaching at the higher education level published between 2012 ...
Micaela Jardim e Silva, Mariana Silva Cecilio, Maurícius Selvero Pazinato   +2 more
wiley   +1 more source

Cryo-EM reveals an extrahelical allosteric binding site at the M5 mAChR

Nature Communications
The M5 muscarinic acetylcholine receptor (M5 mAChR) represents a promising therapeutic target for neurological disorders. However, the high conservation of its orthosteric binding site poses significant challenges for drug development.
Wessel A. C. Burger, Jesse I. Mobbs, Bhavika Rana, Jinan Wang, Keya Joshi, Patrick R. Gentry, Mahmuda Yeasmin, Hariprasad Venugopal, Aaron M. Bender, Craig W. Lindsley, Yinglong Miao, Arthur Christopoulos, Celine Valant, David M. Thal   +13 more
doaj   +1 more source

Investigation of allosteric regulation of porcine fructose-1,6-bisphosphatase

, 2007
Jian Lü
openalex   +2 more sources

Differential regulation of STP, LTP and LTD by structurally diverse NMDA receptor subunit-specific positive allosteric modulators

, 2021
Grace France, Rasa Volianskis, Rachael Ingram, Neil Bannister, R. Rothärmel, Mark W. Irvine, G. Fang, Erica S. Burnell, Kiran Sapkota, Blaise M. Costa, Divija Chopra, Shashank M. Dravid, Adina T. Michael‐Titus, Daniel T. Monaghan, John Georgiou, Zuner A. Bortolotto, David E. Jane, Graham L. Collingridge, Arturas Volianskis   +18 more
openalex   +1 more source

Periodontitis treatment and microbiome in a patient with FAM20A mutation: Case study of 1.5 years

Clinical Advances in Periodontics, EarlyView.
Abstract Background Enamel‐renal‐gingival syndrome (ERGS) is an autosomal recessive disorder caused by mutations in the FAMily with sequence similarity 20A (FAM20A) gene, and is characterized by amelogenesis imperfecta, delayed or failed tooth eruption, and periodontitis.
John Rong Hao Tay, Preethi Balan, Chaminda Jayampath Seneviratne   +2 more
wiley   +1 more source

Rational Design Strategies for Stimuli‐Responsive DNAzymes Using Modified and Artificial Nucleotides

Chemistry – A European Journal, EarlyView.
Activity control of RNA‐cleaving DNAzymes in response to external stimuli has attracted growing interest for applications in DNA‐based diagnostics, therapeutics, and dynamic DNA nanotechnology. This review summarizes rational design strategies for stimuli‐responsive DNAzymes using modified or artificial nucleotides, including split and caged DNAzymes ...
Yusuke Takezawa, Mitsuhiko Shionoya
wiley   +1 more source

Engineering allosteric regulation into the hinge region of a circularly permuted TEM-1 β-lactamase [PDF]

, 2010
Valéry Mathieu, Jacques Fastrez, Patrice Soumillion   +2 more
openalex   +1 more source