Results 171 to 180 of about 127,473 (347)

Allosteric regulation of the 16 alpha-hydroxylation of progesterone as catalyzed by rabbit microsomal cytochrome P-450 3b.

, 1983
Eric F. Johnson, George Schwab, Hermann H. Dieter   +2 more
openalex   +1 more source

Crystallographic studies of ribonucleotide reductase fromSalmonella typhimurium. Clues about the allosteric regulation [PDF]

, 2002
Malin Uppsten, Mathias Färnegård, H. Eklund, Ulla Uhlin   +3 more
openalex   +1 more source

Considerations for drug trials in hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1095-1112, April 2025.
Abstract Hypertrophic cardiomyopathy (HCM) is a heterogeneous condition with potentially serious manifestations. Management has traditionally comprised therapies to palliate symptoms and implantable cardioverter‐defibrillators to prevent sudden cardiac death. The need for disease‐modifying therapies has been recognized for decades.
John P. Farrant, Matthias Schmitt, Anna B. Reid, Clifford J. Garratt, William G. Newman, Aneil Malhotra, Rhys Beynon, Masliza Mahmod, Betty Raman, Robert M. Cooper, Dana Dawson, Thomas Green, Sanjay K. Prasad, Anvesha Singh, Susanna Dodd, Hugh Watkins, Stefan Neubauer, Christopher A. Miller   +17 more
wiley   +1 more source

Emerging maps of allosteric regulation in cellular networks. [PDF]

Curr Opin Struct Biol, 2023
Mathy CJP, Kortemme T.
europepmc   +1 more source

Computational modelling of myocardial metabolism in patients with advanced heart failure

European Journal of Heart Failure, EarlyView.
LV, left ventricular; LVAD, left ventricular assist device; LVEF, left ventricular ejection fraction. Abstract Aims Perturbations of myocardial metabolism and energy depletion are well‐established hallmarks of heart failure (HF), yet methods for their systematic assessment remain limited in humans.
Niklas Beyhoff, Vera M. Braun, Marieluise Kirchner, Lucy E.M. Finnigan, Christoph Knosalla, István Baczkó, Evgenij Potapov, Ulrich Kintscher, Tilman Grune, Titus Kuehne, Hermann‐Georg Holzhütter, Philipp Mertins, Damian J. Tyler, Hendrik Milting, Betty Raman, Oliver J. Rider, Stefan Neubauer, Nikolaus Berndt   +17 more
wiley   +1 more source

Allosteric regulation of the access channels to the Rb+ occlusion sites of (Na+ + K+)-ATPase.

, 1993
Jan Hasenauer, W.H. Huang, Amir Askari
openalex   +1 more source

Identification of Regions of the Tomato γ-Glutamyl Kinase That Are Involved in Allosteric Regulation by Proline [PDF]

, 2003
Tomomichi Fujita, Albino Maggio, Mario G. García-Ríos, Cynthia V. Stauffacher, Ray A. Bressan, László N. Csonka   +5 more
openalex   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Allosteric regulation and inhibition of protein kinases. [PDF]

Biochem Soc Trans, 2023
Mingione VR, Paung Y, Outhwaite IR, Seeliger MA.   +3 more
europepmc   +1 more source

Allosteric regulation of tRNA import: interactions between tRNA domains at the inner membrane of Leishmania mitochondria [PDF]

, 2003
Srikanta Goswami
openalex   +1 more source