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Allosteric regulation, cooperativity, and biochemical oscillations
Biophysical Chemistry, 1990Allosteric regulation is associated with a number of periodic phenomena in biochemical systems. The cooperative nature of such regulatory interactions provides a source of nonlinearity that favors oscillatory behavior. We assess the role of cooperativity in the onset of biochemical oscillations by analyzing two specific examples.
Goldbeter, Albert, Dupont, Geneviève
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An engineered chorismate mutase with allosteric regulation
Bioorganic & Medicinal Chemistry, 2003Besides playing a central role in phenylalanine biosynthesis, the bifunctional P-protein in Eschericia coli provides a unique model system for investigating whether allosteric effects can be engineered into protein catalysts using modular regulatory elements.
Sheng Zhang, Bruce Ganem, David Wilson
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An Allosterically Regulated Molecular Shuttle
Angewandte Chemie International Edition, 2006Dana S. Marlin +3 more
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Ribonucleotide Reductases: The Evolution of Allosteric Regulation
Archives of Biochemistry and Biophysics, 2002Ribonucleotide reductases catalyze in all living organisms the production of the deoxyribonucleotides required for DNA replication and repair. Their appearance during evolution was a prerequisite for the transition from the "RNA world," where RNA sufficed for both catalysis and information transfer, to today's situation where life depends on the ...
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Enhancing global access to cancer medicines
Ca-A Cancer Journal for Clinicians, 2020Javier Cortés +2 more
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An Allosteric Ribozyme Regulated by Doxycyline
Angewandte Chemie, 2000Vincent Thuillier +3 more
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Doping regulation in transition metal compounds for electrocatalysis
Chemical Society Reviews, 2021Jie Zeng +2 more
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Environmental Regulation and Enterprise Innovation: A Review
Business Strategy and the Environment, 2020Dabo Guan, Shuai Shao, Zhigao Hu
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