Results 81 to 90 of about 63,430 (242)
Structural basis for allosteric substrate specificity regulation in anaerobic ribonucleotide reductases [PDF]
Derek T. Logan+3 more
openalex +1 more source
Objective Podocytes are integral to the maintenance of the glomerular filtration barrier. Their injury results in proteinuria and disease progression in lupus nephritis (LN). Aberrant IgG glycosylation drives podocyte injury in LN and leads to cytoskeletal rearrangement, motility changes, and decreased nephrin production.
Rhea Bhargava+9 more
wiley +1 more source
Crystallographic studies of ribonucleotide reductase fromSalmonella typhimurium. Clues about the allosteric regulation [PDF]
Malin Uppsten+3 more
openalex +1 more source
Antiphospholipid Syndrome: An Antibody‐Mediated Disease With Emerging Therapeutic Opportunities
Antiphospholipid syndrome (APS) is an autoimmune thromboinflammatory disease characterized by vascular thrombosis, pregnancy morbidity, and other manifestations driven by antiphospholipid autoantibodies. In this review, we present a clinical case that illustrates some diagnostic and therapeutic challenges in managing severe, relapsing APS ...
Thalia G. Newman, Jason S. Knight
wiley +1 more source
Differential regulation of nitric oxide synthases and their allosteric regulators in heart and vessels of hypertensive rats [PDF]
Aleksandra Piech+4 more
openalex +1 more source
The lipoprotein transport system (Lol) is a crucial target for combating multidrug‐resistant gram‐negative bacteria. This review discusses the structural and functional aspects of the LolABCDE complex, recent advances in small‐molecule inhibitors, and challenges, such as permeability and resistance.
Saemee Song, Su Yong Shim
wiley +1 more source
Emerging maps of allosteric regulation in cellular networks. [PDF]
Mathy CJP, Kortemme T.
europepmc +1 more source
Allosteric regulation of the access channels to the Rb+ occlusion sites of (Na+ + K+)-ATPase.
Jan Hasenauer, W.H. Huang, Amir Askari
openalex +1 more source