Discovery of Hit Compounds Targeting the P4 Allosteric Site of K-RAS, Identified through Ensemble-Based Virtual Screening. [PDF]
J Chem Inf Model, 2023 Gomez-Gutierrez P +2 more
europepmc +1 more source
Targeting an allosteric site in dynamin-related protein 1 to inhibit Fis1-mediated mitochondrial dysfunction. [PDF]
Nat Commun, 2023 Rios L +5 more
europepmc +1 more source
The N-Terminus of Human Sulfotransferase 2B1b─a Sterol-Sensing Allosteric Site. [PDF]
Biochemistry, 2022 Cook I, Leyh TS.
europepmc +1 more source
A single allosteric site merges activation, modulation and inhibition in TRPM5. [PDF]
Nat Chem BiolRuan Z +5 more
europepmc +1 more source
Allosteric Site of ACE-2 as a Drug Target for COVID-19. [PDF]
ACS Pharmacol Transl Sci, 2022 Dutta K.
europepmc +1 more source
Galectin-3 Binds to the Allosteric Site and Activates Integrins αvβ3, αIIbβ3, and α5β1, and Lactose Inhibits This Activation. [PDF]
BiomoleculesTakada YK, Wan YY, Takada Y.
europepmc +1 more source
Illumination of serotonin transporter mechanism and role of the allosteric site. [PDF]
Sci Adv, 2021 Yang D, Gouaux E.
europepmc +1 more source
Characterisation of an allosteric site in PLCγ enzymes and implications for development of their specific inhibitors. [PDF]
Biochem JBunney TD +11 more
europepmc +1 more source
2-(Trihydroxyphenyl)thienopyrimidinones as Key Scaffolds for Targeting a Novel Allosteric Site of HIV-1 Integrase. [PDF]
MoleculesTocco G +6 more
europepmc +1 more source
A Conserved Allosteric Site on Drug-Metabolizing CYPs: A Systematic Computational Assessment. [PDF]
Int J Mol Sci, 2021 Fischer A, Smieško M.
europepmc +1 more source