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Allosteric Binding Sites on Muscarinic Acetylcholine Receptors
Molecular Pharmacology, 2005 In this issue of Molecular Pharmacology, Tränkle et al. (p. 1597) present new findings regarding the existence of a second allosteric site on the M2 muscarinic acetylcholine receptor (M2 mAChR). The M2 mAChR is a prototypic class A G protein-coupled receptor (GPCR) that has proven to be a very useful model system to study the molecular mechanisms ...openaire +2 more sourcesPredicting Binding Sites by Analyzing Allosteric Effects
2011 This chapter describes a method for analyzing the allosteric influence of molecular interactions on protein conformational distributions. The method, called Dynamics Perturbation Analysis (DPA), generally yields insights into allosteric effects in proteins and is especially useful for predicting ligand-binding sites.Dengming, Ming, Michael E, Wallopenaire +2 more sourcesAllosteric Site
2010 Jean-Michel Scherrmann, Kim Wolff, Christine A. Franco, Marc N. Potenza, Tayfun Uzbay, Lisiane Bizarro, David C. S. Roberts, Robert L. Balster, Sharon L. Walsh, Barbara J. Mason, Charles J. Heyser, Anthony L. Riley, Steve Kohut, Marie-Louise G. Wadenberg, Heather Wilkins, Paul Newhouse, Anne Jackson, Joachim D. Uys, Peter W. Kalivas, Victoria L. Harvey, Tony Dickenson, Daniel Bertrand, Hans Rollema, Raymond S. Hurst, Gorkem Yararbas, Sakire Pogun, Marie-Louise G. Wadenberg, Debby Van Dam, Peter Paul De Deyn, Samuel G. Siris, Richard W. Foltin, Michael J. Kuhar, Robert L. Balster, Sharon L. Walsh, Robert L. Balster, Sharon L. Walsh, Michel Le Moal, Christoph Hiemke, Nicola Simola, Micaela Morelli, Nicola Simola, Micaela Morelli, Nicola Simola, Micaela Morelli, Alyson J. Bond, James J. Strain, R. Andrew Chambers, R. H. De Rijk, E. R. de Kloet, Bankole A. Johnson, Andreas Marneros, Suzanne H. Mitchell, Harriet de Wit, Mark Slifstein, Klaus A. Miczek, Rosa M. M. de Almeida, Emil F. Coccaro, David S. Baldwin, John Atack, Hilde Lavreysen, Rosa M. M. de Almeida, Klaus A. Miczek, Alyson J. Bond, Alfonso Abizaid, Shimon Amir, Samuel G. Siris, Joseph H. Friedman, Theodora Duka, Jelena Nesic, Falk Kiefer, Karl Mann, Bankole A. Johnson, Barbara J. Mason, Charles J. Heyser, Karl Mann, Falk Kiefer, Christopher L. Cunningham, Barbara J. Mason, Charles J. Heyser, Yesne Alici, William Breitbart, Subhash C. Pandey, Karl Mann, Falk Kiefer, Kieran O’Malley, Kieran O’Malley, Mitul A. Mehta, Linda Dykstra, John Atack, Hilde Lavreysen, Debby Van Dam, Peter Paul De Deyn, Holden D. Brown, Michael E. Ragozzino, Brian E. Leonard, Malcolm Lader, Peter J. Flor, Inga D. Neumann, Linda P. Spear, Holden D. Brown, Michael E. Ragozzino, Daniel Hoyer, Martina de Zwaan, Michael J. Owens, Chase H. Bourke, Philip J. Cowen, Pedro L. Delgado, Hiroyuki Uchida, Shitij Kapur, Harriet de Wit, Lawrence H. Price, Malcolm Lader, Husseini K. Manji, Jorge A. Quiroz, Seiya Miyamoto, Francisco Aboitiz, Ximena Carrasco, F. Xavier Castellanos, Michael J. Owens, Chase H. Bourke, Elizabeth C. Warburton, Husseini K. Manji, Jorge A. Quiroz, Linda Dykstra, James H. Woods, Mei-Chuan Ko, Gail Winger, Andrew Young, Jill B. Becker, Helen J. Cassaday, Paul Willner, Maria Isabel Colado, A. Richard Green, Marilyn E. Carroll, Peter A. Santi, Iván Izquierdo, Lia R. Bevilaqua, Martin Cammarota, Alfonso Abizaid, Shimon Amir, Jason C. G. Halford, Arthur Christopoulos, Gregory D. Stewart, Patrick M. Sexton, Sheldon Preskorn, Megan M. Dahmen, Jana Lincoln, Edoardo Spina, Brian E. Leonard, J. Craig Nelson, Meghan M. Grady, Stephen M. Stahl, Thomas R. E. Barnes, Michael M. Morgan, MacDonald J. Christie, Linda Dykstra, Joseph H. Friedman, Marie-Louise G. Wadenberg, Wiepke Cahn, Heleen B. M. Boos, H. D. Postma, Seiya Miyamoto, W. Wolfgang Fleischhacker, Samuel B. Hutton, Peter J. Flor, Inga D. Neumann, Inga D. Neumann, Peter J. Flor, Peter J. Flor, Inga D. Neumann, Grasielle C. Kincheski, Leandro J. Bertoglio, Antonio Pádua Carobrez, Helio Zangrossi, Frederico Guilherme Graeff, James Winslow, Yogita Chudasama, Paul Newhouse, Heather Wilkins, Naheed (Max) Mirza, Shuang Yu, Nuno Sousa, Osborne F. X. Almeida, Osborne F. X. Almeida, Nuno Sousa, Shuang Yu, Osborne F. X. Almeida, Nuno Sousa, Shuang Yu, Tim C. Kirkham, Tim C. Kirkham, Jason C. G. Halford, Ronald F. Mucha, Cecilia J. Hillard, Cecilia J. Hillard, Kim Wolff, Fiona Thomson, Susan Napier, Marie-Louise G. Wadenberg, Craig A. Erickson +199 moreopenaire +1 more source
