Results 61 to 70 of about 423,347 (319)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
, 2021 Modeling of software-intensive systems using formal declarative modeling languages offers a means of managing software complexity through the use of abstraction and early identification of correctness issues by formal analysis. Alloy is one such language
Eid, Elias
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Micromechanisms of short fatigue crack growth in an Al-Si piston alloy [PDF]
, 2014 The short fatigue crack growth behaviour of a model cast aluminium piston alloy has been investigated. This has been achieved using a combination of fatigue crack replication methods at various intervals during fatigue testing and post-mortem analysis of
T.O. Mbuya +3 more
core +1 more source
Alloying Motif Confined in Intercalative Frameworks toward Rapid Li‐Ion Storage
Advanced Science, 2022 High‐capacity alloying‐type anodes suffer poor rate capability due to their great volume expansion, while high‐rate intercalation‐type anodes are troubled with low theoretical capacity.
Xueyu Lin +6 more
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
The influence of laser assistance on the machinability of the titanium alloy Ti555-3 [PDF]
, 2013 The Ti533-3 alloy is a new titanium alloy which is starting to see increased use in the aeronautical domain to improve the durability of components and to optimize the weight/resistance ratio. This alloy is characterized by greater resistance compared to
GERMAIN, Guénaël +3 more
core +1 more source
Metals, 2017 Adsorption of hydrogen on Al(111), Cu(111), Mg(0001), and Ti(0001) surfaces have been investigated by means of first principles calculation. The calculation of surface energy indicates that Mg(0001) is the most stable surface, while Ti(0001) is the most ...
Yu Liu +3 more
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source