Results 1 to 10 of about 24,640 (168)

In silico evaluation of garlic-derived organosulfur compounds as multi-target inhibitors of breast cancer biomarkers. [PDF]

PLoS ONE
Breast cancer is the leading cause of cancer mortality among women globally, and drug resistance complicates treatment. Garlic-derived organosulfur compounds exhibit anticancer potential, but their multi-target activity against key breast cancer ...
Courage Siame, Benedict Ofori, Lily Paemka, Kwabena Owusu Danquah   +3 more
doaj   +2 more sources

Chemical Studies on Some Chromone Derivatives with Anticipated Pharmaceutical Applications: Thesis Abstract [PDF]

Egyptian Journal of Cancer and Biomedical Research, 2021
The present study reports a convenient protocol for the design and synthesis of new heterocyclic compounds incorporating 1- hydroxy-naphthyl and new angular chromones bearing allylnaphthyl fragments.
Aya El-Sawi, Eman Keshk, Abdelrahman Abdelrahman, El-Sayed El-Desoky   +3 more
doaj   +1 more source

Chemical studies of some fused heterocyclic compounds containing oxygen with anticipated biological interests: Thesis Abstract [PDF]

Egyptian Journal of Cancer and Biomedical Research, 2021
Thesis AbstractBackground: Heterocyclic are known to have multiple applications in particular biomedical settings. Aim: The present study reports a convenient protocol for the design and synthesis of new heterocyclic compounds incorporating 1- hydroxy ...
Abdelrahman Abdelrahman, El-Sayed El-Desoky, Mohamed Abozeid, Aya El-Sawi   +3 more
doaj   +1 more source

Design, synthesis, and SAR study of isopropoxy allylbenzene derivatives as 15-lipoxygenase inhibitors [PDF]

Iranian Journal of Basic Medical Sciences, 2020
Objective(s): Allylbenzenes have been recently developed as inhibitors of lipoxygenases. They decrease peroxidation activity via mimicking 1,4-unsaturated bonds of fatty acids by their allyl portion.
Mina Mousavian, Seyed Jamal Alavi, Raheleh Rahbarian, Majid Rajabian, Hossein Orafai, Hamid Sadeghian   +5 more
doaj   +1 more source

Comparative Analysis of Volatile Flavor Compounds in Seven Mustard Pastes via HS-SPME–GC–MS

Molecules, 2023
To identify the volatile flavor components in mustard paste (MP), the volatile compounds in seven MPs available on the market were isolated and analyzed by headspace solid-phase microextraction combined with gas chromatography–mass spectrometry.
Miao Liang, Rui Wang, Yajian Wu, Runhu Xin, Wei Guan, Yuping Liu   +5 more
doaj   +1 more source

Nitrile Oxide, Alkenes, Dipolar Cycloaddition, Isomerization and Metathesis Involved in the Syntheses of 2-Isoxazolines

Molecules, 2023
The involvement of 1,3-dipolar cycloaddition (1,3-DP), double bond migration, metathesis, and nitrile oxide (including in situ-generated nitrile oxide) as dipoles, together with the C=C bond containing dipolarophiles, in the syntheses of 2-isoxazolines ...
Stanisław Krompiec, Piotr Lodowski, Aneta Kurpanik-Wójcik, Bogumiła Gołek, Angelika Mieszczanin, Aleksandra Fijołek, Marek Matussek, Klaudia Kaszuba   +7 more
doaj   +1 more source

Chemical Constituents, In Vitro Antioxidant Activity and In Silico Study on NADPH Oxidase of Allium sativum L. (Garlic) Essential Oil

Antioxidants, 2021
Allium sativum L., also known as garlic, is a perennial plant widely used as a spice and also considered a medicinal herb since antiquity. The aim of this study was to determine by gas chromatography–mass spectrometry (GC–MS) the chemical profile ...
Oscar Herrera-Calderon, Luz Josefina Chacaltana-Ramos, Irma Carmen Huayanca-Gutiérrez, Majed A. Algarni, Mohammed Alqarni, Gaber El-Saber Batiha   +5 more
doaj   +1 more source

A Novel Family of [1,4]Thiazino[2,3,4-ij]quinolin-4-ium Derivatives: Regioselective Synthesis Based on Unsaturated Heteroatom and Heterocyclic Compounds and Antibacterial Activity

Molecules, 2021
A novel family of [1,4]thiazino[2,3,4-ij]quinolin-4-ium derivatives was synthesized by annulation reactions of 8-quinolinesulfenyl chloride with unsaturated heteroatom and heterocyclic compounds.
Vladimir A. Potapov, Roman S. Ishigeev, Lyudmila A. Belovezhets, Svetlana V. Amosova   +3 more
doaj   +1 more source

Synthesis of Some Phenolic and Amino derivatives of Cinchoninic Acid [PDF]

مجلة التربية والعلم, 2008
Treatment of cinchoninic acids (1a,b) with allyl bromide afforded compounds (2a,b), and the hydrolysis of (2a) gave the 2-(4`-allyloxyphenyl) cinchoninic acid (4) .
M. A. Al-Iraqi, K Al-Naimi, A Al- Sabawi
doaj   +1 more source

Bioactive Compounds in Dietary Spices and Medicinal Plants [PDF]

Journal of Agronomy, Technology and Engineering Management, 2022
Aim of this review is to show the most important bioactive compounds in hot spices such as black pepper (Piper nigrum L.), chilli pepper (Capsicum annuum L.) and medicinal plant such AS garlic (Allium sativum L.), and its modes of action ...
Nikola Puvača
doaj   +1 more source