Results 61 to 70 of about 139,835 (302)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Almost sure convergence of randomised‐difference descent algorithm for stochastic convex optimisation

open access: yesIET Control Theory & Applications, 2021
Stochastic gradient descent algorithm is a classical and useful method for stochastic optimisation. While stochastic gradient descent has been theoretically investigated for decades and successfully applied in machine learning such as training of deep ...
Xiaoxue Geng, Gao Huang, Wenxiao Zhao
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Almost Everywhere Convergence of Convolution Measures [PDF]

open access: yes, 2012
Let (X, ℬ, m, τ) be a dynamical system with (X, ℬ, m) a probability space and τ an invertible, measure preserving transformation. This paper deals with the almost everywhere convergence in L1(X) of a sequence of operators of weighted averages.
Karin Reinhold   +2 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

DOUBLE WEIGHTED LACUNARY ALMOST STATISTICAL CONVERGENCE OF ORDER α [PDF]

open access: yesRomanian Journal of Mathematics and Computer Science, 2016
In this paper, we define and study the concept of double weighted lacunary almost statistical convergence of order α. Further, some inclusion relations have been examined.
SUKRAN KONCA, EKREM SAVAS, SELMAN EKIN
doaj  

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

open access: yesFEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile   +8 more
wiley   +1 more source

Some weak type inequalities and almost everywhere convergence of Vilenkin–Nörlund means

open access: yesJournal of Inequalities and Applications, 2023
We prove and discuss some new weak type ( 1 , 1 ) $(1,1 ) $ inequalities of maximal operators of Vilenkin–Nörlund means generated by monotone coefficients. Moreover, we use these results to prove a.e. convergence of such Vilenkin–Nörlund means.
Davit Baramidze   +3 more
doaj   +1 more source

ON \(\Lambda\)-CONVERGENCE ALMOST EVERYWHERE OF MULTIPLE TRIGONOMETRIC FOURIER SERIES

open access: yesUral Mathematical Journal, 2017
We consider one type of convergence of multiple trigonometric Fourier series intermediate between the convergence over cubes and the \(\lambda \)-convergence for \(\lambda >1\).
Nikolai Yu. Antonov
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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