Results 61 to 70 of about 139,835 (302)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Stochastic gradient descent algorithm is a classical and useful method for stochastic optimisation. While stochastic gradient descent has been theoretically investigated for decades and successfully applied in machine learning such as training of deep ...
Xiaoxue Geng, Gao Huang, Wenxiao Zhao
doaj +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Almost Everywhere Convergence of Convolution Measures [PDF]
Let (X, ℬ, m, τ) be a dynamical system with (X, ℬ, m) a probability space and τ an invertible, measure preserving transformation. This paper deals with the almost everywhere convergence in L1(X) of a sequence of operators of weighted averages.
Karin Reinhold +2 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
DOUBLE WEIGHTED LACUNARY ALMOST STATISTICAL CONVERGENCE OF ORDER α [PDF]
In this paper, we define and study the concept of double weighted lacunary almost statistical convergence of order α. Further, some inclusion relations have been examined.
SUKRAN KONCA, EKREM SAVAS, SELMAN EKIN
doaj
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile +8 more
wiley +1 more source
Some weak type inequalities and almost everywhere convergence of Vilenkin–Nörlund means
We prove and discuss some new weak type ( 1 , 1 ) $(1,1 ) $ inequalities of maximal operators of Vilenkin–Nörlund means generated by monotone coefficients. Moreover, we use these results to prove a.e. convergence of such Vilenkin–Nörlund means.
Davit Baramidze +3 more
doaj +1 more source
ON \(\Lambda\)-CONVERGENCE ALMOST EVERYWHERE OF MULTIPLE TRIGONOMETRIC FOURIER SERIES
We consider one type of convergence of multiple trigonometric Fourier series intermediate between the convergence over cubes and the \(\lambda \)-convergence for \(\lambda >1\).
Nikolai Yu. Antonov
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source

