RNA‐related functions of BRCA2 in transcription, replication, and genome stability
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
DOUBLE WEIGHTED LACUNARY ALMOST STATISTICAL CONVERGENCE OF ORDER α [PDF]
In this paper, we define and study the concept of double weighted lacunary almost statistical convergence of order α. Further, some inclusion relations have been examined.
SUKRAN KONCA, EKREM SAVAS, SELMAN EKIN
doaj
Some weak type inequalities and almost everywhere convergence of Vilenkin–Nörlund means
We prove and discuss some new weak type ( 1 , 1 ) $(1,1 ) $ inequalities of maximal operators of Vilenkin–Nörlund means generated by monotone coefficients. Moreover, we use these results to prove a.e. convergence of such Vilenkin–Nörlund means.
Davit Baramidze +3 more
doaj +1 more source
Afterpop: the Almost Perfect Convergence [PDF]
This paper focuses on one of the newest notions in Spanish literary theory created by Eloy Fernández Porta in his work Afterpop. La literatura de la implosion mediatica (2007). The theorist reaches for the aesthetical accomplishments of postmodernism, avant-pop and cyberpunk in order to analyze them in the context of the new artistic mentality from the
openaire +5 more sources
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
ON \(\Lambda\)-CONVERGENCE ALMOST EVERYWHERE OF MULTIPLE TRIGONOMETRIC FOURIER SERIES
We consider one type of convergence of multiple trigonometric Fourier series intermediate between the convergence over cubes and the \(\lambda \)-convergence for \(\lambda >1\).
Nikolai Yu. Antonov
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Almost sure exponential stability of numerical solutions for stochastic delay differential equations [PDF]
Using techniques based on the continuous and discrete semimartingale convergence theorems, this paper investigates if numerical methods may reproduce the almost sure exponential stability of the exact solutions to stochastic delay differential equations (
Szpruch, Lukasz, Wu, Fuke, Mao, Xuerong
core +3 more sources
Probabilistic norms and statistical convergence of random variables [PDF]
The paper extends certain stochastic convergence of sequences of Rk -valued random variables (namely, the convergence in probability, in Lp and almost surely) to the context of E-valued random variables.
Mohamad Rafi Segi Rahmat +1 more
doaj

