Results 81 to 90 of about 2,239,568 (291)
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
General Weak Laws of Large Numbers for Bootstrap Sample Means [PDF]
AMS classifications: 60F05, 62G09; 62G20.Bootstrap sample mean;weak law of large numbers;convergence in probability;almost certain ...
Einmahl, J.H.J., Rosalsky, A.
core
A note about almost uniform convergence on D-poset of intuitionistic fuzzy sets [PDF]
Notes on IFSThe aim of this contribution is studying the almost uniform convergence on D-poset of intuitionistic fuzzy sets. We prove the connection between almost everywhere convergence of random variables in Kolmogorov probability space and almost uniform ...
Katarína Čunderlíková
doaj +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Rate of Convergence of Predictive Distributions for Dependent Data [PDF]
This paper deals with empirical processes of the type Cn(B) = n^(1/2) {µn(B) - P(Xn+1 in B | X1, . . . ,Xn)} , where (Xn) is a sequence of random variables and µn = (1/n)SUM(i=1,..,n) d(Xi) the empirical measure.
Pietro Rigo +3 more
core
Mean and Almost Everywhere Convergence of Fourier–Neumann Series [PDF]
, 1999 Let Jμ denote the Bessel function of order μ. The functions x−α/2−β/2−1/2Jα+β+2n+1(x1/2), n=0,1,2,…, form an orthogonal system in L2((0,∞),xα+βdx) when α+β>−1. In this paper we analyze the range of p, α, and β for which the Fourier series with respect to
José J. Guadalupe +14 more
core +1 more source
Strong and Weak Convergence for Asymptotically Almost Negatively Associated Random Variables
Discrete Dynamics in Nature and Society, 2013 The strong law of large numbers for sequences of asymptotically almost negatively associated (AANA, in short) random variables is obtained, which generalizes and improves the corresponding one of Bai and Cheng (2000) for independent and identically ...
Aiting Shen, Ranchao Wu
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source