Results 121 to 130 of about 9,980,026 (286)
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Sidon sets and Sidon-partitions in cyclic groups through almost different sets
Procedia Computer Science, 2023 Luis-Miguel Delgado +3 more
openaire +1 more source
THE ALMOST IDEAL SUPPLY SYSTEM AND AGRICULTURAL PRODUCTION IN THE UNITED STATES [PDF]
This paper estimates an Almost Ideal Supply System using aggregate U.S. agricultural data. Share equations derived from an indirect production function yield elasticities that are consistent with production theory.
Hilmer, Christiana E., Holt, Matthew T.
core
Fuzzy Soft Sets and its Application to Decision Making: A Short Case Study Involving the Health Sector [PDF]
The health sector faces uncertainty and complex decision-making scenarios, making traditional analytical tools insufficient. The fuzzy soft set theory has emerged as a powerful framework for modeling and reasoning with uncertain information, with ...
Adebisi, Sunday Adesina +1 more
core +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
When almost all sets are difference dominated in $\mathbb{Z}/n\mathbb{Z}$
, 2016 We investigate the behavior of the sum and difference sets of $A \subseteq \mathbb{Z}/n\mathbb{Z}$ chosen independently and randomly according to a binomial parameter $p(n) = o(1)$. We show that for rapidly decaying $p(n)$, $A$ is almost surely difference-dominated as $n \to \infty$, but for slowly decaying $p(n)$, $A$ is almost surely balanced as $n ...
Hemmady, Anand +2 more
openaire +3 more sources
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
A Survey of Courses Set-up for Clinical Nurse Specialists in China
Huli yanjiu, 2004 Objective: in order to provide a basis both for courses set-up to meet the needs of the situation and for fostering clinical nurse specialists suggestions of clinical nursing staffs, nursing administration staffs, and professional nursing teachers on the
王欣, 王惠珍
doaj
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source