Results 41 to 50 of about 358,966 (246)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

The changing views on the evolutionary relationships of extant Salamandridae (Amphibia: Urodela). [PDF]

open access: yesPLoS ONE, 2018
The phylogenetic relationships among members of the family Salamandridae have been repeatedly investigated over the last 90 years, with changing character and taxon sampling. We review the changing composition and the phylogenetic position of salamandrid
Michael Veith   +3 more
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

The expression of quantity in Oneida: a study in syntactic and semantic variation

open access: yesLinguistic Typology
One of the questions linguists try to answer is to what extent conceptual content is expressed similarly across languages. The null hypothesis is that languages express the same sorts of things but may differ in the particular morphological and syntactic
Koenig Jean-Pierre, Michelson Karin
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

DIETARY VEGETABLE PROTEIN IN BROILER FEEDING [PDF]

open access: yesJournal of Animal and Poultry Production, 2004
The performance of broiler chicks fed plant-protein-diets ( starter, grower, finisher ) was compared to those fed diets supplemented with 5% meat and bone meal, (67% protein). One hundred and sixty, one day old male Ross broilers, were used.
T. EI- Afifi, H. Motawe, Akila Saleh,
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

The ASSIST trial: Acute effects of manipulating strength exercise volume on insulin sensitivity in obese adults: A protocol for a randomized controlled, crossover, clinical trial.

open access: yesPLoS ONE
Type 2 diabetes mellitus is a disease in which insulin action is impaired, and an acute bout of strength exercise can improve insulin sensitivity.
Luis Filipe Rocha Silva   +8 more
doaj   +1 more source

Soil quality evaluation under different land use types in Kersa sub-watershed, eastern Ethiopia

open access: yesEnvironmental Systems Research, 2021
Background Soil quality, which can be inferred using indicators that interact synergistically, is affected by land use types and agricultural management practices. This study assessed the status of soil quality under three adjacent land uses (cultivated,
Yared Mulat   +3 more
doaj   +1 more source

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