Results 101 to 110 of about 1,771,045 (277)
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Almost increasing sequences and their new applications II
Filomat, 2014 In this paper, we generalize a known theorem dealing with |C,?|k summability factors to the |C,?,?,?|k summability factors of infinite series. This theorem also includes some known and new results.
openaire +2 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
ZooKeys, 2011 Specimens of Starksia were collected throughout the western Atlantic, and a 650-bp portion of the mitochondrial gene cytochrome oxidase-c subunit I (COl) was sequenced as part of a re-analysis of species diversity of western Central Atlantic shorefishes.
Carole Baldwin +3 more
doaj +1 more source
, 2020 We introduce a tropical version of the Fukaya algebra of a Lagrangian submanifold and use it to show that tropical Lagrangian tori are weakly unobstructed.
Venugopalan, Sushmita, Woodward, Chris
core
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
The EDGE-CALIFA Survey: Molecular Gas and Star Formation Activity across the Green Valley
The Astrophysical JournalWe present a ^12 CO( J = 2−1) survey of 60 local galaxies using data from the Atacama Compact Array as part of the Extragalactic Database for Galaxy Evolution: the ACA EDGE survey.
Vicente Villanueva +13 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Analysis of heat shock transcription factor gene family in cocoa
Pesquisa Agropecuária TropicalThe heat shock factor (HSF) is crucial for plant stress regulation. This study aimed to analyze the role and characteristics of the HSF protein in Theobroma cacao L. The assesment was carried out bioinformatically, consisting of
Waki’atil Rosida +2 more
doaj +1 more source