Results 111 to 120 of about 7,550,048 (276)
A General Type of Almost Contact Manifolds [PDF]
Among almost contact manifolds Sasakian manifolds, Kenmotsu manifolds (called also “a certain class of almost contact manifolds”) and cosymplectic manifolds have been studied by many authors.
Catalin Angelo Ioan
core
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
The Set of Idempotents in the Weakly Almost Periodic Compactification of the Integers is not Closed [PDF]
, 2000 This paper answers negatively the question of whether the sets of idempotents in the weakly almost periodic compacti?cations of (N; +) and (Z; +) are ...
Pym, J.S., Bordbar, Behzad
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A new note on almost increasing and quasi monotone sequences
Filomat, 2014 In [22], we proved a main theorem dealing an application of almost increasing and quasi monotone sequences. In this paper, we prove that theorem under weaker conditions. We also obtained some new and known results.
openaire +2 more sources
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
On almost B-summable double sequence spaces
, 2018 The concept of a four-dimensional generalized difference matrix and its domain on some double sequence spaces was recently introduced and studied by Tuğ and Başar (AIP Conference Proceedings, vol. 1759, 2016) and Tuğ (J. Inequal. Appl. 2017(1):149, 2017).
Orhan Tuğ
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Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source