Results 131 to 140 of about 8,222,439 (341)
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Izkoriščanje sončne energije na Krasu : Solar energy exploitation on Kras [PDF]
Geodetski Vestnik, 2007 The article discusses solar energy exploitation on Kras, one of the sunniest Slovenian regions. GIS methods were used to assemble a decision tree model that provided areas most suitable for solar energy exploitation.
Klemen Zakšek +2 more
doaj
Open Problem: Best Arm Identification: Almost Instance-Wise Optimality and the Gap Entropy Conjecture [PDF]
, 2016 Lijie Chen, Jian Li
openalex +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Stationary solutions for a Schrodinger-Poisson system in R^3
Electronic Journal of Differential Equations, 2002 Under appropriate, almost optimal, assumptions on the data we prove existence of standing wave solutions for a nonlinear Schr"odinger equation in the entire space $mathbb{R}^3$ when the real electric potential satisfies a linear Poisson equation.
Khalid Benmlih
doaj
An Almost Optimal Rank Bound for Depth-3 Identities [PDF]
, 2011 Nitin Saxena, C. Seshadhri
openalex +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Optimal Linear Shrinkage Estimator for Large Dimensional Precision Matrix
, 2014 In this work we construct an optimal shrinkage estimator for the precision matrix in high dimensions. We consider the general asymptotics when the number of variables $p\rightarrow\infty$ and the sample size $n\rightarrow\infty$ so that $p/n\rightarrow c\
Bodnar, Taras +2 more
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