Results 111 to 120 of about 4,545,606 (290)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Quick eVALUATION OF THE INTERVAL STABILITY OF THE LINEAR ASSIGNMENT problem SOLUTIONS

open access: yesДоклады Белорусского государственного университета информатики и радиоэлектроники, 2019
An efficient algorithm for evaluating the interval of solutions stability of opened and closed linear assignment problems based on a review of the results of optimization iterations is proposed. Economical one-step transition to the nearest vertex of the
M. P. Revotjuk   +2 more
doaj  

Optimality Notions for Resolvent Monte Carlo

open access: yesMathematics
Resolvent Monte Carlo estimates eigenvalues of large matrices by sampling Markov chains and reading the target value off a truncated resolvent quotient, trading exact arithmetic for a stochastic error that the almost-optimal sampling scheme is designed ...
Tsvetelin Kostadinov, Ivan T. Dimov
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Almost Optimal Distribution-free Junta Testing

open access: yesCoRR, 2019
arXiv admin note: text overlap with arXiv:1802.04859 by other ...
openaire   +6 more sources

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Construction of zero correlation zone Gaussian integer sequence set

open access: yesTongxin xuebao, 2017
The construction of zero correlation zone (ZCZ) Gaussian integer sequence set was researched.Based on binary orthogonal matrices,ZCZ ternary sequence sets were constructed by adding zeros at first.Then the ternary ZCZ squences were transformed into ...
Yu-bo LI, Jia-an SUN, Nan JING
doaj   +2 more sources

Sosiaalisen median markkinointistrategia Almost New Oy:lle [PDF]

open access: yes
Työssä kehitettiin Almost New Oy:lle systemaattinen ja mitattava sosiaalisen median markkinointistrategia, jonka tavoitteena oli vahvistaa yrityksen brändiä, lisätä asiakassitoutumista ja tukea liiketoiminnan kasvua.
Luotonen, Santeri
core  

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Almost sure exponential stability of backward Euler–Maruyama discretizations for hybrid stochastic differential equations [PDF]

open access: yes, 2011
This is a continuation of the first author's earlier paper [1] jointly with Pang and Deng, in which the authors established some sufficient conditions under which the Euler-Maruyama (EM) method can reproduce the almost sure exponential stability of the ...
Shen, Yi, Mao, Xuerong, Gray, Alison
core   +2 more sources

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