Results 91 to 100 of about 4,545,606 (290)
On the Weighted Mixed Almost Unbiased Ridge Estimator in Stochastic Restricted Linear Regression
Journal of Applied Mathematics, 2013 We introduce the weighted mixed almost unbiased ridge estimator (WMAURE) based on the weighted mixed estimator (WME) (Trenkler and Toutenburg 1990) and the almost unbiased ridge estimator (AURE) (Akdeniz and Erol 2003) in linear regression model.
Chaolin Liu, Hu Yang, Jibo Wu
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Optimal Stochastic Control Problem for General Linear Dynamical Systems in Neuroscience
Advances in Mathematical Physics, 2017 This paper considers a d-dimensional stochastic optimization problem in neuroscience. Suppose the arm’s movement trajectory is modeled by high-order linear stochastic differential dynamic system in d-dimensional space, the optimal trajectory, velocity ...
Yan Chen +3 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Optimal quantum states for frequency estimation
New Journal of Physics, 2014 We investigate different quantum parameter estimation scenarios in the presence of noise, and identify optimal probe states. For frequency estimation of local Hamiltonians with dephasing noise, we determine optimal probe states for up to 70 qubits, and ...
F Fröwis +3 more
doaj +1 more source
Folk Theorems with Bounded Recall under (Almost) Perfect Monitoring, Second Version [PDF]
A strategy profile in a repeated game has bounded recall L if play under the profile after two distinct histories that agree in the last L periods is equal.
George J. Mailath, : Wojciech Olszewski
core
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Construction of Resilient Functions with High Nonlinearity and Optimal Algebraic Degree
四川大学学报. 自然科学版, 2017 Resilient Boolean functions with good nonlinearity and optimal algebraic degree play an important role in the design and analysis of stream cipher and block ciphers.
LIU Qian, WANG Huai-Zhu, ZHANG Li-Na
doaj
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Jurnal Educatio: Jurnal Pendidikan Indonesia, 2018 Student learning outcomes are low and not optimal is a common problem that occurs in adolescents in almost all schools in Indonesia. One reason, teachers are less than optimal in accommodating student learning styles.
Yuyun Mashurwati
doaj +1 more source