Results 81 to 90 of about 701,199 (295)
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
About the cause of the stimulative effect of humate in yeast cultures
Acta Societatis Botanicorum Poloniae, 2015 Trials were undertaken to elucidate the stimulating effect of sodium humate on yeast multiplication and the intensity of their fermentation. This effect appears specifically at pH non-optimal for the medium.
S. Gumiński, J. Sulej
doaj +1 more source
Optimal quantum query bounds for almost all Boolean functions [PDF]
, 2012 We show that almost all n-bit Boolean functions have bounded-error quantum query complexity at least n/2, up to lower-order terms. This improves over an earlier n/4 lower bound of Ambainis (A.
Smotrovs, J. +15 more
core +1 more source
An Almost Optimal Algorithm for Computing Nonnegative Rank [PDF]
SIAM Journal on Computing, 2013 Summary: Here, we give an algorithm for deciding if the nonnegative rank of a matrix \(M\) of dimension \(m \times n\) is at most \(r\) which runs in time \((nm)^{O(r^2)}\). This is the first exact algorithm that runs in time singly exponential in \(r\).
openaire +3 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Book review “Innovation Culture in Crony Capitalism: Does Hofstede’s Model Matter?”
Ekonomski Vjesnik, 2020 Optimal innovation culture enables a strong entrepreneurial economy with a high innovative potential and improved competitiveness on international markets. What is it that determines innovation culture?
Predrag Bejaković
doaj
STOCHASTIC GROWTH WITH NONCONVEXITIES:THE OPTIMAL CASE [PDF]
This paper studies optimal investment and dynamic behaviour of stochastically growing economies. We assume neither convex technology nor bounded support of the productivity shocks. A number of basic results concerning the investment policy and the Ramsey–
Kazuo Nishimura +2 more
core
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Folk Theorems with Bounded Recall under (Almost) Perfect Monitoring, Second Version [PDF]
A strategy profile in a repeated game has bounded recall L if play under the profile after two distinct histories that agree in the last L periods is equal.
George J. Mailath, : Wojciech Olszewski
core
Almost Optimal Testers for Concise Representations
CoRR, 2019 We give improved and almost optimal testers for several classes of Boolean functions on $n$ inputs that have concise representation in the uniform and distribution-free model. Classes, such as $k$-junta, $k$-linear functions, $s$-term DNF, $s$-term monotone DNF, $r$-DNF, decision list, $r$-decision list, size-$s$ decision tree, size-$s$ Boolean formula,
openaire +5 more sources