Results 61 to 70 of about 4,545,606 (290)
Almost-Optimal Gossip-Based Aggregate Computation [PDF]
SIAM Journal on Computing, 2012 Motivated by applications to modern networking technologies, there has been interest in designing efficient gossip-based protocols for computing aggregate functions. While gossip-based protocols provide robustness due to their randomized nature, reducing the message and time complexity of these protocols is also of paramount importance in the context ...
Jen-Yeu Chen, Gopal Pandurangan
openaire +3 more sources
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Expander Decomposition with Almost Optimal Overhead
CoRRWe present the first polynomial-time algorithm for computing a near-optimal \emph{flow}-expander decomposition. Given a graph $G$ and a parameter $ϕ$, our algorithm removes at most a $ϕ\log^{1+o(1)}n$ fraction of edges so that every remaining connected component is a $ϕ$-\emph{flow}-expander (a stronger guarantee than being a $ϕ$-\emph{cut}-expander ...
Nikhil Bansal 0001 +2 more
openaire +4 more sources
Optimal spatial field control for controlled release ‡
, 2020 SUMMARY Most distributed parameter control problems involve manipulation within the spatial domain. Such problems arise in a variety of applications including epidemiology, tissue engineering, and cancer treatment.
Optim, Optimal
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Robust monetary policy in a currency union [PDF]
Panoeconomicus, 2012 A great number of recent researches have found importance of country specific shocks for optimal monetary policy construction in the context of a currency union.
Kuznetsova Olga
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Optimal States and Almost Optimal Adaptive Measurements for Quantum Interferometry [PDF]
Physical Review Letters, 2000 4 pages, 4 figures, journal ...
Berry, D. W., Wiseman, H. M.
openaire +5 more sources
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Electronic Journal of Differential Equations, 2015 In this article, we are interested in singularly perturbed nonlinear elliptic problems involving a fractional Laplacian. Under a class of nonlinearity which is believed to be almost optimal, we construct a positive solution which exhibits multiple ...
Jinmyoung Seok
doaj