Results 131 to 140 of about 1,064,326 (320)

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Choquard equations with recurrent potentials

Advances in Nonlinear Analysis
In this article, we are concerned with the existence of nontrivial solutions to the Choquard equation −Δu+α(x)u=(∣x∣−μ∗∣u∣q)∣u∣q−2uinRN(N≥2),-\Delta u+\alpha \left(x)u=\left({| x| }^{-\mu }\ast {| u| }^{q}){| u| }^{q-2}u\hspace{1.0em}\hspace{0.1em}\text ...
Ding Hui-Sheng, Liu Quan, Long Wei, Zhong Lan   +3 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Periodicity of almost periodic zero sets and almost periodic functions

, 2015
7 pages, 8 ...
openaire   +2 more sources

Weighted pseudo almost periodic functions, convolutions and abstract integral equations

, 2016
This paper deals with a systematic study of the convolution operator K f = f ⁎ k defined on weighted pseudo almost periodic functions space PAP ( X , ρ ) and with k ∈ L 1 ( R ) .
A. Coronel, M. Pinto, Daniel Sepúlveda
semanticscholar   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Pseudo Asymptotic Behavior of Mild Solution for Nonautonomous Integrodifferential Equations with Nondense Domain

Journal of Applied Mathematics, 2014
By the weighted ergodic function based on the measure theory, we study pseudo asymptotic behavior of mild solution for nonautonomous integrodifferential equations with nondense domain.
Zhinan Xia
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Various Grids in Moiré Measurements

Metrology
The moiré effect is typically observed in regular periodic structures and sometimes in random (aperiodic) structures. However, currently, only regular graphical objects are used in measurements. We propose using graphical objects that are not regular but
Vladimir Saveljev
doaj   +1 more source