Results 111 to 120 of about 7,009,663 (303)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Factorization of Almost Periodic Matrix Functions

Journal of Mathematical Analysis and Applications, 1995
Let \(AP\) be the space of Bohr almost periodic functions \(f(x) \sim \sum_j f_j e^{i \lambda_j x}\). Let \(\widehat f (\lambda) = M(e^{- i \lambda x} f(x))\) and \(\Omega (f) = \{\lambda \in \mathbb{R} : \widehat f (\lambda) \neq 0\}\), \(\mathbb{R}_\pm = \{x \in \mathbb{R} : \pm x \geq 0\}\), \(AP^\pm = \{f \in AP : \Omega (f) \subset\mathbb{R}_\pm\}\
Karlovich, Y., Spitkovsky, I.
openaire   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Choquard equations with recurrent potentials

Advances in Nonlinear Analysis
In this article, we are concerned with the existence of nontrivial solutions to the Choquard equation −Δu+α(x)u=(∣x∣−μ∗∣u∣q)∣u∣q−2uinRN(N≥2),-\Delta u+\alpha \left(x)u=\left({| x| }^{-\mu }\ast {| u| }^{q}){| u| }^{q-2}u\hspace{1.0em}\hspace{0.1em}\text ...
Ding Hui-Sheng, Liu Quan, Long Wei, Zhong Lan   +3 more
doaj   +1 more source

δ-Almost Periodic Functions and Applications to Dynamic Equations

Mathematics, 2019
In this paper, by employing matched spaces for time scales, we introduce a δ -almost periodic function and obtain some related properties. Also the hull equation for homogeneous dynamic equation is introduced and results of the existence are ...
Chao Wang, Ravi P. Agarwal, Donal O’Regan   +2 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Various Grids in Moiré Measurements

Metrology
The moiré effect is typically observed in regular periodic structures and sometimes in random (aperiodic) structures. However, currently, only regular graphical objects are used in measurements. We propose using graphical objects that are not regular but
Vladimir Saveljev
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Subharmonic almost periodic functions

, 2005
We prove that almost periodicity in the sense of distributions coincides with almost periodicity with respect to Stepanov's metric for the class of subharmonic functions in a strip {z belongs C : a < Imz < b}.
Favorov, S.Yu., Rakhnin, A.V.
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source