Results 101 to 110 of about 1,064,326 (320)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Almost Periodic Solution of a Multispecies Discrete Mutualism System with Feedback Controls

open access: yesDiscrete Dynamics in Nature and Society, 2015
We consider an almost periodic multispecies discrete Lotka-Volterra mutualism system with feedback controls. We firstly obtain the permanence of the system by utilizing the theory of difference equation.
Hui Zhang   +3 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Structure of the Set of Bounded Solutions and Existence of Pseudo Almost Periodic Solutions of a Vector Liénard Differential Equation

open access: yesNonautonomous Dynamical Systems, 2019
We give sufficient conditions ensuring the existence and uniqueness of pseudo almost periodic solution of the vectorial Liénard ’s equation.
E. Ait Dads, Cieutat P., Lhachimi L.
doaj   +1 more source

(VC)(n)-ALMOST PERIODIC FUNCTIONS

open access: yesDemonstratio Mathematica, 1999
Let \(V(t; f)\) be the variation of a function \(f\in C^{(n)}(\mathbb{R})\) on the interval \(\langle t-1,t+1\rangle\). Let \[ (VD)^{(n)}(f)= \sup_{t\in\mathbb{R}} \sum^n_{k=0} (|f^{(k)}(t)|+ V(t; f^{(k)})). \] Following the definition of almost periodicity with almost periods defined by means of the norm \((VD)^{(n)}(f)\), there is defined and ...
openaire   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Problem for hyperbolic system of equations having constant coefficients with integral conditions with respect to the time variable

open access: yesKarpatsʹkì Matematičnì Publìkacìï, 2014
In a domain specified in the form of a Cartesian product of a segment $\left[0,T\right]$ and the space ${\mathbb R}^{p}$, we study a problem with integral conditions with respect to the time variable for  hyperbolic system with constant coefficients in a
A.M. Kuz, B.Yo. Ptashnyk
doaj   +1 more source

Global convergence dynamics of almost periodic delay Nicholson's blowflies systems

open access: yesJournal of Biological Dynamics, 2020
We take into account nonlinear density-dependent mortality term and patch structure to deal with the global convergence dynamics of almost periodic delay Nicholson's blowflies system in this paper.
Chuangxia Huang, Renli Su, Yuhui Hu
doaj   +1 more source

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