Results 81 to 90 of about 498,134 (298)

Controls of nucleosome positioning in the human genome.

PLoS Genetics, 2012
Nucleosomes are important for gene regulation because their arrangement on the genome can control which proteins bind to DNA. Currently, few human nucleosomes are thought to be consistently positioned across cells; however, this has been difficult to ...
Daniel J Gaffney, Graham McVicker, Athma A Pai, Yvonne N Fondufe-Mittendorf, Noah Lewellen, Katelyn Michelini, Jonathan Widom, Yoav Gilad, Jonathan K Pritchard   +8 more
doaj   +1 more source

MODELING HEAT EXCHANGE DEPENDING ON THE PRANDTL NUMBER FOR VARIOUS GEOMETRIC AND REGIME PARAMETERS

Вестник Дагестанского государственного технического университета: Технические науки, 2020
Objectives. The aim is to study the dependency of the distribution of integral heat transfer during turbulent convective heat transfer in a pipe with a sequence of periodic protrusions of semicircular geometry on the Prandtl number using the calculation ...
I. E. Lobanov
doaj   +1 more source

Semiclassical Inequivalence of Polygonalized Billiards

, 2001
Polygonalization of any smooth billiard boundary can be carried out in several ways. We show here that the semiclassical description depends on the polygonalization process and the results can be inequivalent.
A.N. Zemlyakov, A.N. Zemlyakov, D. Biswas, D. Biswas, D. Biswas, D. Biswas, Debabrata Biswas, E. Gutkin, E.B. Bogomolny, E.J. Heller, H. Bruus, J.L. Vega, M. Sieber, M.C. Gutzwiller, N. Pavloff, O. Bohigas, P. Bellomo, P.J. Richens, R. Artuso, T. Cheon, Tomiya   +20 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Entire functions of exponential type represented by pseudo-random and random Taylor series

, 2016
We study the influence of the multipliers $\xi (n)$ on the angular distribution of zeroes of the Taylor series \[ F_\xi (z) = \sum_{n\ge 0} \xi (n) \frac{z^n}{n!}\,.
Borichev, Alexander, Nishry, Alon, Sodin, Mikhail   +2 more
core   +3 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Harmonization of the Activity of the Left and Right Cerebral Hemispheres - an Important Component of the Spiritual and Mental Health of Individual and Humanity

Mental Health, 2020
Introduction According to modern scholars (N. Maslova, B. Astafiev), one of the important reasons for the global planetary crisis, including modern educational system in particular, is violation of the conformity of nature principles in the process of ...
Tamara Tyurina, Sofiya Stavkova
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Psychoacoustic Properties of Fibonacci Sequences

Acta Polytechnica, 2008
1202, Fibonacci set up one of the most interesting sequences in number theory. This sequence can be represented by so-called Fibonacci Numbers, and by a binary sequence of zeros and ones.
J. Sokoll, S. Fingerhuth
doaj