Results 61 to 70 of about 3,600,540 (296)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Precision Aliphatic Polyesters via Segmer Assembly Polymerization
Molecules, 2018 Precise structure-property relation of a biodegradable polymer (e.g., aliphatic polyester) is anticipated only if monomer units and chiral centers are arranged in a defined primary sequence as a biomacromolecule. An emerging synthetic methodology, namely
Fu-Rong Zeng, Yang Liang, Zi-Long Li
doaj +1 more source
Gowers norms for automatic sequences
Discrete Analysis, 2023 Gowers norms for automatic sequences, Discrete Analysis 2023:4, 62 pp. There are several situations in additive and extremal combinatorics where it is useful to decompose an object $X$ into a "structured" part $S(X)$ and a "quasirandom" part $Q(X)$.
Jakub Byszewski +2 more
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Almost Periodic and Asymptotically Almost Periodic Solutions of Liénard Equations [PDF]
, 2011 The aim of this paper is to study the almost periodic and asymptotically almost periodic solutions on (0,+1) of the Li´enard equation x′′ + f(x)x′ + g(x) = F(t), where F : T !
null null +4 more
core +1 more source
Extreme points of the Besicovitch--Orlicz space of almost periodic functions equipped with the Luxemburg norm [PDF]
, 2021 summary:We investigate which points in the unit sphere of the Besicovitch--Orlicz space of almost periodic functions, equipped with the Luxemburg norm, are extreme points.
Boulahia, Fatiha, Hassaine, Slimane
core +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Controls of nucleosome positioning in the human genome.
PLoS Genetics, 2012 Nucleosomes are important for gene regulation because their arrangement on the genome can control which proteins bind to DNA. Currently, few human nucleosomes are thought to be consistently positioned across cells; however, this has been difficult to ...
Daniel J Gaffney +8 more
doaj +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source