Results 81 to 90 of about 569,475 (279)

A non-autonomous impulsive food-chain model with delays

Advances in Difference Equations, 2019
A non-autonomous almost periodic prey–predator system with impulsive effects and multiple delays is proposed in this paper, Holling’s type-IV systems and ratio-dependent functional responses are also involved in the model.
Baodan Tian, Pengkai Zhang, Jiamei Li, Yong Zhang, Liu Yang   +4 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

On reducibility of Quantum Harmonic Oscillator on $\mathbb{R}^d$ with quasiperiodic in time potential

, 2016
We prove that a linear d-dimensional Schr{\"o}dinger equation on $\mathbb{R}^d$ with harmonic potential $|x|^2$ and small t-quasiperiodic potential $i\partial\_t u -- \Delta u + |x|^2 u + \epsilon V (t\omega, x)u = 0, x \in \mathbb{R}^d$ reduces to an ...
Grébert, Benoît, Paturel, Eric
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

On nth-order differential operators with Bohr-Neugebauer type property

International Journal of Mathematics and Mathematical Sciences, 1987
Suppose B is a bounded linear operator in a Banach space. If the differential operator dndtn−B has a Bohr-Neugebauer type property for Bochner almost periodic functions, then, for any Stepanov almost periodic continuous function g(t) and any Stepanov ...
Aribindi Satyanarayan Rao
doaj   +1 more source

New results on positive almost periodic solutions for first-order neutral differential equations

Advances in Difference Equations, 2018
In this paper, a class of first-order neutral differential equations with time-varying delays and coefficients is considered. Some results on the existence of positive almost periodic solutions for the equations are obtained by using the contracting ...
Yuehua Yu, Shuhua Gong
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Robust Almost Periodic Dynamics for Interval Neural Networks with Mixed Time-Varying Delays and Discontinuous Activation Functions

Abstract and Applied Analysis, 2013
The robust almost periodic dynamical behavior is investigated for interval neural networks with mixed time-varying delays and discontinuous activation functions.
Huaiqin Wu, Sanbo Ding, Xueqing Guo, Lingling Wang, Luying Zhang   +4 more
doaj   +1 more source

Almost Periodicity of Mild Solutions of Inhomogeneous Periodic Cauchy Problems

Journal of Differential Equations, 1999
The authors consider a mild solution \(u\) to the well-posed inhomogeneous Cauchy problem \[ u'(t)= A(t)u(t)+ f(t), \] on a Banach space \(X\), where \(A(\cdot)\) is periodic. For a problem on \(\mathbb{R}_+\) the authors show that \(u\) is asymptotically almost-periodic if \(f\) is asymptotically almost-periodic, \(u\) is bounded, uniformly continuous
Batty, C, Hutter, W, Rabiger, F
openaire   +3 more sources