Results 81 to 90 of about 5,189,005 (253)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Almost Periodic Solution of a Multispecies Discrete Mutualism System with Feedback Controls

open access: yesDiscrete Dynamics in Nature and Society, 2015
We consider an almost periodic multispecies discrete Lotka-Volterra mutualism system with feedback controls. We firstly obtain the permanence of the system by utilizing the theory of difference equation.
Hui Zhang   +3 more
doaj   +1 more source

Computation of transfer function matrices of periodic systems [PDF]

open access: yes, 2002
We present a numerical approach to evaluate the transfer function matrices of a periodic system corresponding to lifted state-space representations as constant systems.
A. Varga, Varga, Andras
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Dynamical analysis of almost periodic solution for a multispecies predator-prey model with mutual interference and time delays

open access: yesAdvances in Difference Equations, 2017
In this paper, we build a multispecies predator-prey model with mutual interference and time delays. By means of the comparison theorem, Ascoli theorem and Lebesgue dominated convergence theorem, we establish the sufficient conditions of permanence and ...
Qin Liu   +4 more
doaj   +1 more source

Asymptotically almost periodic and almost periodic solutions for partial neutral differential equations

open access: yesApplied Mathematics Letters, 2005
This paper continues the work of the first author and \textit{H. R. Henríquez} [J. Math. Anal. Appl., 221, 452--475 (1998; Zbl 0915.35110), J. Math. Anal. Appl. 221, No.2, 499--522 (1998; Zbl 0926.35151)] for partial neutral functional-differential equations with unbounded delay, where they considered the existence of solutions and periodic solutions ...
Eduardo Hernández Morales   +1 more
openaire   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Almost periodic solutions of nonlinear hyperbolic equations with time delay

open access: yesElectronic Journal of Differential Equations, 2001
The almost periodicity of bounded solutions is established for a nonlinear hyperbolic equation with piecewise continuous time delay. The equation represents a mathematical model for the dynamics of gas absorption.
Hushang Poorkarimi, Joseph Wiener
doaj  

$C^n$-almost periodic and almost periodic solutions for some nonlinear integral equations

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2012
In this paper, we investigate the existence of $C^n$-almost periodic solution for a class of nonlinear Fredholm integral equations, and the existence of almost periodic solution for a class of nonlinear functional integral equations.
Huisheng Ding   +2 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

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