Results 61 to 70 of about 38,909 (260)

Almost Periodic Solutions of Prey-Predator Discrete Models with Delay

open access: yesAdvances in Difference Equations, 2009
The purpose of this article is to investigate the existence of almost periodic solutions of a system of almost periodic Lotka-Volterra difference equations which are a prey-predator system x1(n+1)=x1(n)exp⁡{b1(n)−a1(n)x1(n)−c2(n ...
Tomomi Itokazu, Yoshihiro Hamaya
doaj   +2 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Existence of generalized almost periodic and asymptotic almost periodic solutions to abstract Volterra integro-differential equations

open access: yesElectronic Journal of Differential Equations, 2017
The main aim of this paper is to study the asymptotic almost periodicity, Stepanov almost periodicity, and asymptotic Stepanov almost periodicity of various classes of regularized solution operator families appearing in the theory of abstract Volterra
Marko Kostic
doaj  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Almost periodic solutions of differential inclusions governed by subdifferentials

open access: yesElectronic Journal of Differential Equations, 2016
Sufficient conditions are given to ensure the existence and eventually the uniqueness of bounded and almost periodic solutions of evolution equations governed by subdifferential operators.
Karim El Mufti
doaj  

Almost periodic solutions of impulsive integro‐differential neural networks

open access: yesMathematical Modelling and Analysis, 2010
In this paper, sufficient conditions are established for the existence of almost periodic solutions for system of impulsive integro‐differential neural networks.
Gani Tr. Stamov, Jehad O. Alzabut
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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