Results 71 to 80 of about 451,129 (278)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Dynamics of μ -piecewise pseudo almost periodic solutions of neutral-type inertial neural networks models: existence and attractiveness. [PDF]

Cogn Neurodyn, 2022
Ezzinbi K, Mbounja Béssémè F.
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

The frequencies of almost periodic solutions of almost periodic differential equations [PDF]

Journal of the Australian Mathematical Society, 1974
AbstractAlmost periodic solutions of a first order almost periodic differential equation in Rp are shown to have less than p basic frequencies additional to the basic frequencies of the almost periodic right hand of the equation.
openaire   +2 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Existence of generalized almost periodic and asymptotic almost periodic solutions to abstract Volterra integro-differential equations

Electronic Journal of Differential Equations, 2017
The main aim of this paper is to study the asymptotic almost periodicity, Stepanov almost periodicity, and asymptotic Stepanov almost periodicity of various classes of regularized solution operator families appearing in the theory of abstract Volterra
Marko Kostic
doaj  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Almost periodic solutions of differential inclusions governed by subdifferentials

Electronic Journal of Differential Equations, 2016
Sufficient conditions are given to ensure the existence and eventually the uniqueness of bounded and almost periodic solutions of evolution equations governed by subdifferential operators.
Karim El Mufti
doaj  

Almost periodic solutions of impulsive integro‐differential neural networks

Mathematical Modelling and Analysis, 2010
In this paper, sufficient conditions are established for the existence of almost periodic solutions for system of impulsive integro‐differential neural networks.
Gani Tr. Stamov, Jehad O. Alzabut
doaj   +1 more source

Almost periodic solution in distribution for stochastic differential equations with Stepanov almost periodic coefficients

, 2017
This paper deals with the existence and uniqueness of ($\mu$-pseudo) almost periodic mild solution to some evolution equations with Stepanov ($\mu$-pseudo) almost periodic coefficients, in both determinist and stochastic cases.
Bedouhene, Fazia, Challali, Nouredine, de Fitte, Paul Raynaud, Mellah, Omar, Smaali, Mannal   +4 more
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