Results 61 to 70 of about 117,196 (345)

Poland Anomaly and Atretic Cephalocele in the Same Child: Coincidence or Association?

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Poland Anomaly is a rare congenital disorder typically characterized by hypoplasia or agenesis of pectoral muscle with or without ipsilateral limb hypoplasia. The association of central nervous system malformation with Poland Anomaly has been rarely reported and includes craniofacial dysplasia, microcephaly, and Dandy‐Walker malformation ...
Alessandra Greta Grassi, Silvia Pontesilli, Laura Demelas, Francesca Vigliani, Massimo Agosti, Angelo Selicorni   +5 more
wiley   +1 more source

Serum Zinc Concentration in Patients with Alopecia Areata

Acta Dermato-Venereologica, 2023
Alopecia areata is an autoimmune non-scarring disease in which the exact mechanism that induces loss of immune privilege is unknown. Zinc is important for DNA stability and repair mechanisms that are essential in maintaining normal hair growth.
Jovan Lalosevic, Mirjana Gajic-Veljic, Jelena Lalosevic Misovic, Milos Nikolic   +3 more
doaj   +1 more source

Repurposing With Purpose: Treatment of Bachmann–Bupp Syndrome With Eflornithine and Implications for Other Polyaminopathies

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Rare diseases impact approximately 1 in 10 people worldwide, and yet, less than 5% of all rare diseases currently have an approved treatment option available. This is due to many challenges unique to rare diseases, including small, diverse patient populations, the cost of drug development that is not proportionate to the number of patients who
Caleb P. Bupp, Elizabeth A. VanSickle, Julianne Michael, Chad R. Schultz, Kelly Nguyen, Melissa Hoefer, Surender Rajasekaran, André S. Bachmann   +7 more
wiley   +1 more source

Vitiliginous alopecia masquerading as frontal fibrosing alopecia

International Journal of Trichology, 2015
A 73‑year‑old female presented at the Dermatology Department with a white shiny band‑like patch on the temporal and forehead zones [Figure 1]. She had a 4‑year history of vulvar lichen scleroatrophicus (LSA) [Figure 2]. Polarized dermoscopy examination revealed follicular ostium preservation, yellow dots and poliosis of vellus hair [Figure 3]...
Pigem, Ramon, Villablanca, Salvador, Podlipnik, Sebastian, Alós i Hernández, Llúcia, Puig i Sardà, Susana   +4 more
openaire   +5 more sources

Decoding regulatory programs underlying placode and dermal condensate cell fate commitment during hair follicle induction via single‐cell multi‐omics analysis

Animal Research and One Health, EarlyView.
The experimental framework of the study encompasses sample collection, single‐cell data analysis, and experimental validation. Abstract Understanding differences in chromatin state and changes in gene regulatory landscape of placode (Pc) and dermal condensate are crucial for decoding hair follicle (HF) morphogenesis programs.
Fang Li, Minghao Li, Tongtong Zhang, Menghua Sui, Hasan Khatib, Xin Wang   +5 more
wiley   +1 more source

A phase II basket trial of dual anti‐CTLA‐4 and anti‐PD‐1 blockade in rare tumors (DART) SWOG S1609: durable responses and delayed pseudoprogression in small cell carcinoma of the ovary, hypercalcemic type cohort

Cancer Communications, EarlyView.
Abstract Background The combined use of anti‐programmed cell death protein 1 (PD‐1)/anti‐cytotoxic T‐lymphocyte associated protein 4 (CTLA‐4) checkpoint inhibitors has been effective in various cancer types. The Southwest Oncology Group (SWOG) Dual Anti‐CTLA‐4 and Anti‐PD‐1 Blockade in Rare Tumors (DART) S1609 study investigated ipilimumab and ...
Young Kwang Chae, Megan Othus, Sandip Pravin Patel, Raid Aljumaily, Khine Z. Win, Tanya Pejovic, Sajeve S. Thomas, William R. Robinson III, Hye Sung Kim, Liam Il‐Young Chung, Christine M. McLeod, Helen X. Chen, Elad Sharon, Howard Streicher, Christopher W. Ryan, Charles D. Blanke, Razelle Kurzrock   +16 more
wiley   +1 more source

Adjuvant capecitabine in combination with docetaxel and cyclophosphamide versus anthracycline plus docetaxel and cyclophosphamide regimen in women with high‐risk, HER2‐negative breast cancer: An open‐label, randomized controlled trial

Cancer Communications, EarlyView.
Abstract Background The standard adjuvant chemotherapy for early‐stage, high‐risk breast cancer includes anthracyclines and taxanes. While anthracycline‐based regimens have proven effective in human epidermal growth factor receptor 2 (HER2)‐positive breast cancer, their efficacy may be reduced in HER2‐negative patients due to the lack of co ...
Yu Song, Yingjiao Wang, Xi Cao, Ying Xu, Yidong Zhou, Qiang Sun, Songjie Shen   +6 more
wiley   +1 more source

Effects of Seasonality and Pregnancy on Hair Loss and Regrowth in Rhesus Macaques

Animals
Several studies have examined the etiology of alopecia, or hair loss, in rhesus macaques. While outcomes differ across studies, some commonalities have emerged. Females, particularly pregnant females, show more alopecia than males, and alopecia follows a
Allison Heagerty, Rebecca A. Wales, Kristine Coleman   +2 more
doaj   +1 more source

Folliculotropic mycosis fungoides: clinical and histologic features in five patients

Indian Journal of Dermatology, 2016
Background: Alopecia can be a manifestation of mycosis fungoides (MF); however, the prevalence is unknown. Aims: We sought to describe the clinicopathologic presentation of alopecia in patients with diagnosis of MF.
Amir Hooshang Ehsani, Arghavan Azizpour, Pedram Noormohammadpoor, Hasan Seirafi, Farshad Farnaghi, Kambiz Kamyab-Hesari, Mehdi Sharifi, Maryam Nasimi   +7 more
doaj   +1 more source

Chinese SLE Treatment and Research Group Registry (CSTAR) XIII: prevalence and risk factors for chronic scarring alopecia in patients with systemic lupus erythematosus

Arthritis Research & Therapy, 2021
Background Scarring alopecia in systemic lupus erythematosus (SLE) patients caused reduced life quality and prolonged disease course. This case-control study aims to survey the prevalence of scarring alopecia during the disease course of SLE and evaluate
Yirong Xiang, Mengtao Li, Hui Luo, Yanhong Wang, Xinwang Duan, Cheng Zhao, Feng Zhan, Zhenbiao Wu, Hongbin Li, Min Yang, Jian Xu, Wei Wei, Lijun Wu, Hanxiao You, Junyan Qian, Xiaoxi Yang, Can Huang, Jiuliang Zhao, Qian Wang, Xiaomei Leng, Xinping Tian, Yan Zhao, Xiaofeng Zeng   +22 more
doaj   +1 more source