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Therapeutische Umschau, 2002 Die Alopecia areata ist eine häufige Krankheit. Die genaue Ursache ist weiterhin nicht klar, auch wenn Hinweise für eine T-zellvermittelte Autoimmunkrankheit bestehen. Genetische, immunologische und psychologische Faktoren spielen eine Rolle. Klinisch handelt es sich meistens um einzelne Zonen nicht vernarbenden Haarausfalls, welche unter einfachen ...
C.-M. Höring, U. Gieler
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Is Intralesional Methotrexate an Effective Alternative to Intralesional Triamcinolone in Alopecia Areata? Findings From a Randomized Controlled Trial. [PDF]
J Cosmet DermatolABSTRACT Background Alopecia areata (AA) is an autoimmune condition resulting in hair loss, sometimes just in small patches but occasionally across larger areas like the entire scalp. For localized AA, treatments often involve injecting corticosteroids, such as triamcinolone acetonide (TrA), directly into the affected areas.
Ghandi N +5 more
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Der Hautarzt, 2013 The epidemiology of alopecia areata as well as murine models of this disease and genome-wide association studies support the concept of alopecia areata as an autoimmune disease. In addition, the genome-wide association studies have led to the identification of new potential therapeutic targets such as CTLA4; these results have already led to the ...
H.F. Merk, V. von Felbert
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Przegląd Dermatologiczny, 2023 The existence of two types of alopecia areata is suggested (probably genetically different): early-onset, with more severe symptoms, longer disease duration, higher tendency to relapse, often with a positive family history, and late-onset, in which the ...
Adriana Rakowska +8 more
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Przegląd Dermatologiczny, 2023 The treatment goal in alopecia areata is induction of hair regrowth and halting the progression of the disease. Treatment decisions depend on the severity of the alopecia areata as assessed by the Severity of Alopecia Tool (SALT) or the Alopecia Areata ...
Adriana Rakowska +8 more
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Progress in immune pathogenesis and targeted therapy of alopecia areata
Pifu-xingbing zhenliaoxue zazhi, 2023 Alopecia areata is a common clinical non-cicatricial alopecia. Alopecia totalis and generalized alopecia may occur in severe cases. The pathogenesis of alopecia areata is complex, and the treatment is faced with many difficulties.
Jiali WANG +3 more
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Nature Reviews Disease Primers, 2017 Alopecia areata is an autoimmune disorder characterized by transient, non-scarring hair loss and preservation of the hair follicle. Hair loss can take many forms ranging from loss in well-defined patches to diffuse or total hair loss, which can affect all hair-bearing sites. Patchy alopecia areata affecting the scalp is the most common type.
Pratt, C Herbert +4 more
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Acta Dermato-Venereologica, 2022 Alopecia areata and depression tend to co-occur; however, their temporal association has not been comprehensively investigated. The aim of this study was to examine the temporal association between alopecia areata and depression.
Dana Tzur Bitan +4 more
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Serum Zinc Concentration in Patients with Alopecia Areata
Acta Dermato-Venereologica, 2023 Alopecia areata is an autoimmune non-scarring disease in which the exact mechanism that induces loss of immune privilege is unknown. Zinc is important for DNA stability and repair mechanisms that are essential in maintaining normal hair growth.
Jovan Lalosevic +3 more
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