Results 11 to 20 of about 74,305 (343)
Der Hautarzt, 2013 The epidemiology of alopecia areata as well as murine models of this disease and genome-wide association studies support the concept of alopecia areata as an autoimmune disease. In addition, the genome-wide association studies have led to the identification of new potential therapeutic targets such as CTLA4; these results have already led to the ...
H.F. Merk, V. von Felbert
+7 more sources
Progress in immune pathogenesis and targeted therapy of alopecia areata
Pifu-xingbing zhenliaoxue zazhi, 2023 Alopecia areata is a common clinical non-cicatricial alopecia. Alopecia totalis and generalized alopecia may occur in severe cases. The pathogenesis of alopecia areata is complex, and the treatment is faced with many difficulties.
Jiali WANG +3 more
doaj +1 more source
Baricitinib for the Treatment of Alopecia Areata
Drugs, 2023 Alopecia areata (AA) is a relapsing, chronic, immune-mediated disease characterized by nonscarring, inflammatory hair loss that can affect any hair-bearing site. AA clinical presentation is heterogeneous.
Egídio Freitas +2 more
semanticscholar +1 more source
Nature Reviews Disease Primers, 2017 Alopecia areata is an autoimmune disorder characterized by transient, non-scarring hair loss and preservation of the hair follicle. Hair loss can take many forms ranging from loss in well-defined patches to diffuse or total hair loss, which can affect all hair-bearing sites. Patchy alopecia areata affecting the scalp is the most common type.
Pratt, C Herbert +4 more
openaire +5 more sources
Acta Dermato-Venereologica, 2022 Alopecia areata and depression tend to co-occur; however, their temporal association has not been comprehensively investigated. The aim of this study was to examine the temporal association between alopecia areata and depression.
Dana Tzur Bitan +4 more
doaj +1 more source
An Updated Review on Current Treatment of Alopecia Areata and Newer Therapeutic Options
International Journal of Trichology, 2023 Alopecia areata (AA) is a dermatological disease that causes nonscarring hair loss. It can occur at any age and has an unpredictable and variable evolution in individuals.
K. Malhotra, Bhushan Madke
semanticscholar +1 more source
Alopecia Areata: Burden of Disease, Approach to Treatment, and Current Unmet Needs
Clinical, Cosmetic and Investigational Dermatology, 2023 Alopecia areata is an autoimmune hair loss disorder with variations in distribution, duration, and severity. The disease is chronic and often follows an unpredictable course, frequently leading to stress and anxiety for those who suffer from it ...
Lina Alhanshali +3 more
semanticscholar +1 more source
Two Phase 3 Trials of Baricitinib for Alopecia Areata.
New England Journal of Medicine, 2022 BACKGROUND Alopecia areata is an autoimmune condition characterized by rapid hair loss in the scalp, eyebrows, and eyelashes, for which treatments are limited.
B. King +15 more
semanticscholar +1 more source
Serum Zinc Concentration in Patients with Alopecia Areata
Acta Dermato-Venereologica, 2023 Alopecia areata is an autoimmune non-scarring disease in which the exact mechanism that induces loss of immune privilege is unknown. Zinc is important for DNA stability and repair mechanisms that are essential in maintaining normal hair growth.
Jovan Lalosevic +3 more
doaj +1 more source