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Alopecia areata: a multifactorial autoimmune condition [PDF]
Alopecia areata is an autoimmune disease that results in non-scarring hair loss, and it is clinically characterised by small patches of baldness on the scalp and/or around the body. It can later progress to total loss of scalp hair (Alopecia totalis) and/
Butcher, John P.+3 more
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Background: Alopecia areata is an autoimmune disorder affecting the hair-bearing sites of the body. Trichoscopy has recently been practiced in the diagnosis of alopecia areata.
Vineet K Sahu+4 more
doaj +1 more source
Establishing and Prioritising Research Questions for the Treatment of Alopecia Areata: The Alopecia Areata Priority Setting Partnership [PDF]
BACKGROUND: Alopecia areata is a common hair loss disorder that results in patchy to complete hair loss. Many uncertainties exist around the most effective treatments for this condition. OBJECTIVES: To identify uncertainties in alopecia areata management
Brockley, J.R.+14 more
core +2 more sources
Alopecia Areata and it’s Association with Thyroid Dysfunction
Background: Out of many cause of non-scarring alopecia, alopecia areata is one the cause of non-scarring alopecia. Most study till now has shown autoimmunity to be pathogenesis of alopecia areata and has found to be frequently associated with abnormal ...
Anjan Rai+3 more
doaj +1 more source
Introduction to Innovations in the Immunology and Clinical Science of Alopecia Areata [PDF]
Alopecia areata is an autoimmune skin disease resulting in the loss of hair on the scalp and elsewhere on the body. The disease most often occurs in childhood and affects males and females of all ages.
Bergfeld, Wilma F.+2 more
core +1 more source
Autoantibodies to Hair Follicles in C3H/HeJ Mice With Alopecia Areata–Like Hair Loss [PDF]
We have previously described spontaneous but reversible hair loss that clinically and histologically resembles human alopecia areata in a colony of C3H/HeJ mice. Alopecia areata in humans is associated with antibodies to hair follicles.
Boggess, Dawnalyn+4 more
core +1 more source
JAK3 as an emerging target for topical treatment of inflammatory skin diseases [PDF]
The recent interest and elucidation of the JAK/STAT signaling pathway created new targets for the treatment of inflammatory skin diseases (ISDs). JAK inhibitors in oral and topical formulations have shown beneficial results in psoriasis and alopecia ...
Alves de Medeiros, Ana+5 more
core +2 more sources
Evidence Based Treatment of Alopecia Areata
Background: Alopecia areata is a chronic autoimmune disease, involving non-scarring hair loss, which affects hair follicles and sometimes nails. Hair loss pattern presents as patchy alopecia, ophiasis, ophiasis inversa (sisapho), reticularis or diffuse ...
Eva Hariani, Nelva K. Jusuf
doaj +1 more source
Tofacitinib in a Recalcitrant Case of Alopecia Areata
Alopecia areata (AA) is a non-cicatricial alopecia that is postulated to be a hair-specific autoimmune disease, with genetic factors playing a role in disease susceptibility and severity.
Mansi Pithadia+3 more
doaj +1 more source
Adiponectin as a novel biomarker of disease severity in alopecia areata
The frequent coexistence of obesity and metabolic syndrome in patients with alopecia areata may indicate the common pathogenetic pathway in these conditions with an important role of adipokines.
Anna Stochmal+6 more
doaj +1 more source