Results 51 to 60 of about 28,373 (234)
Epidemiological Trends in Alopecia Areata at the Global, Regional, and National Levels
Frontiers in Immunology, 2022 BackgroundNo comprehensive studies have been published on the global burden of alopecia areata since 2010.ObjectiveWe aimed to measure the global, regional, and national incidence of alopecia areata and disability-adjusted life-years (DALYs) by age, sex,
Haifeng Wang, Lifang Pan, Yanfeng Wu
doaj +1 more source
Alopecia Areata: Treatment of Today and Tomorrow [PDF]
, 2003 It is the aim of this article to review and appraise available data on treatments for alopecia areata (AA) according to the demands of evidence based medicine. Studies evaluating the efficacy of a treatment for AA should include appropriate controls, use
Freyschmidt-Paul, Pia +3 more
core +1 more source
Comprehensive Safety Exposure‐Response Analysis to Support Ritlecitinib Dose Selection
CPT: Pharmacometrics &Systems Pharmacology, EarlyView.ABSTRACT Ritlecitinib is a kinase inhibitor drug recently approved for the treatment of alopecia areata (AA) in both adults and adolescents based on a single, combined Phase 2b/3 study. Various QD doses with and without a loading dose have been evaluated in the pivotal Phase 2b/3 study.
Yeamin Huh +5 more
wiley +1 more source
Efficacy and safety of methotrexate in alopecia areata [PDF]
Anais Brasileiros de Dermatologia, 2014 BACKGROUND: Alopecia areata is a chronic disorder of the hair follicles and nails, of unknown etiology, with clear autoimmune components and genetic factors.
Mariana Hammerschmidt +1 more
doaj +1 more source
T-cell reconstitution after thymus xenotransplantation induces hair depigmentation and loss [PDF]
, 2013 Here we present a mouse model for T-cell targeting of hair follicles, linking the pathogenesis of alopecia to that of depigmentation disorders. Clinically, thymus transplantation has been successfully used to treat T-cell immunodeficiency in congenital ...
Blundell, MP +7 more
core +3 more sources
The Journal of Dermatology, EarlyView.ABSTRACT Bullous pemphigoid (BP) is the most common autoimmune blistering skin disease worldwide. In the difficult‐to‐treat BP or if standard therapies are contraindicated, the use of biologics may be also considered although there is no strong evidence supporting their use.
Gianluca Avallone +50 more
wiley +1 more source
Dermatology Practical & ConceptualIntroduction: Alopecia areata is a type of non-scarring alopecia, which is thought to be associated with T-cell mediated immune response. Objective: This study aims to compare the levels of serum inflammatory markers before and after treatment in ...
Icim Komurcugil, Nermin Karaosmanoğlu
doaj +1 more source
Trichoscopy criteria for diagnosing female androgenic alopecia. [PDF]
, 2008 Differential diagnosis of chronic hair loss remains a challenge in dermatology. The aim of the study was to evaluate the value of a new scalp visualization technique, trichoscopy, in differential diagnosis of hair loss.
Adriana Rakowska +4 more
core +1 more source
The Journal of Dermatology, EarlyView.ABSTRACT Background Acute diffuse and total alopecia (ADTA) is a variant of alopecia areata (AA) that lacks the typical patchy hair loss seen in classical AA and presents with an acute onset of diffuse hair loss. It has a favorable prognosis. Objectives The purpose of this study was to assess the role of T‐helper (Th) 17 cells and regulatory T cells ...
Ji‐Hoon Lim +4 more
wiley +1 more source
The role of extracellular vesicles in cutaneous remodeling and hair follicle dynamics [PDF]
, 2019 Extracellular vesicles (EVs), including exosomes, microvesicles, and apoptotic bodies, are cell-derived membranous structures that were originally catalogued as a way of releasing cellular waste products.
Carrasco, Elisa +2 more
core +2 more sources