Results 91 to 100 of about 3,522 (243)

Case report: Dupilumab therapy for alopecia areata in a 4-year-old patient resistant to baricitinib

open access: yesFrontiers in Medicine, 2023
Alopecia areata (AA) is a non-scarring hair loss disorder. Alopecia totalis (AT) and alopecia universalis (AU) are the severe subtypes of AA. Age of onset before 6 years of age, disease duration of more than 1 year, and extensive alopecia involving more ...
Lu Cai   +7 more
doaj   +1 more source

Childhood alopecia areata: What treatment works best? [PDF]

open access: yes, 2011
There are no validated effective treatments for alopecia areata (AA). Topical immunotherapy (squaric acid dibutylester [SADBE] and diphenylcyclopropenone [DPCP]) induces the most significant short-term hair regrowth in children with severe AA (strength ...
Haynes, James W.   +2 more
core  

Alopecia areata: a new treatment plan [PDF]

open access: yes, 2011
Many therapeutic modalities have been used to treat alopecia areata, with variable efficacy and safety profiles. Unfortunately, none of these agents is curative or preventive.
Alsantali, Adel
core   +3 more sources

A fresh look at augmenter of liver regeneration in rats. [PDF]

open access: yes, 1999
Augmenter of liver regeneration (ALR) is a hepatotrophic protein originally identified by bioassay in regenerating rat and canine livers following partial hepatectomy and in the hyperplastic livers of weanling rats, but not in resting adult livers.
Abyss   +86 more
core   +1 more source

Clinical heterogeneity in vitiligo: Identification of clinical markers based patient clusters

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Vitiligo is a chronic autoimmune disease with heterogeneous clinical presentations. This study analysed 399 patients using hierarchical clustering and identified five phenotypes based on clinical characteristics and lesion distribution. Two groups exhibited high disease activity and extensive involvement.
Laura Galissi   +8 more
wiley   +1 more source

Frictional alopecia of the distal legs: case series and review [PDF]

open access: yes, 2016
BackgroundAcquired alopecia of the lower legs may occur secondary to friction due to socks, footwear, or both on the lower extremities. There is scant literature that reports on this phenomenon.Methods and MaterialsWe describe 5 patients who presented ...
Cohen, Philip R, Zhao, Johnny
core   +2 more sources

Adipose Tissue‐Derived Exosomes in the Treatment of Lichen Planopilaris: A Case Report

open access: yesClinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Adipose‐derived exosomes may offer a novel therapeutic approach for lichen planopilaris (LPP) unresponsive to standard treatments, with preliminary evidence suggesting potential benefits in symptom control and hair preservation.
Mohammad Ali Nilforoushzadeh   +4 more
wiley   +1 more source

The Use of Light‐Based Therapies in the Treatment of Alopecia

open access: yesJournal of Cosmetic Dermatology, Volume 24, Issue 9, September 2025.
ABSTRACT Background Alopecia encompasses a group of conditions that can significantly impact quality of life, especially among women and younger individuals. While pharmaceutical therapies remain the cornerstone of treatment, laser and light‐based therapies, especially low‐level light therapy (LLLT), offer promising noninvasive alternatives.
Robert J. Vanaria   +2 more
wiley   +1 more source

Multiomics Analysis of the Response to Ritlecitinib in Alopecia Areata Subtypes and Correlation With Efficacy

open access: yesAllergy, Volume 80, Issue 8, Page 2348-2360, August 2025.
Ritlecitinib modulated Type I/II immunity genes (CCL5, CD8A, GZMB, CCL13, CCL18, and IL13RA1), MoA genes (JAK3, ITK, and BTK), and upregulated hair keratins, with stronger effects in AAP than AT/AU. Baseline and longitudinal scalp and serum protein changes correlated with hair regrowth and disease improvement.
Li Xi   +6 more
wiley   +1 more source

Is Intralesional Methotrexate an Effective Alternative to Intralesional Triamcinolone in Alopecia Areata? Findings From a Randomized Controlled Trial

open access: yesJournal of Cosmetic Dermatology, Volume 24, Issue 8, August 2025.
ABSTRACT Background Alopecia areata (AA) is an autoimmune condition resulting in hair loss, sometimes just in small patches but occasionally across larger areas like the entire scalp. For localized AA, treatments often involve injecting corticosteroids, such as triamcinolone acetonide (TrA), directly into the affected areas.
Narges Ghandi   +5 more
wiley   +1 more source

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