A schematic representation illustrating the preparation of BGNP@YM and its therapeutic effects on septic mice induced by lipopolysaccharide (LPS). (A) BBR is first encapsulated within GNPs to form BGNPs with anti‐inflammatory activity, which are subsequently coated with YM via chemical precipitation to obtain the BGNP@YM oral delivery system.
Qing‐Qing Dong +6 more
wiley +1 more source
Alpha-amylase and Alpha-glucosidase enzymes inhibition and antioxidant potential of selected medicinal plants used as anti-diabetes by Sundanese community in West Java, Indonesia. [PDF]
Febriyanti RM +5 more
europepmc +1 more source
ABSTRACT Depression in adolescents and young adults is common, associated with substantial functional impairment and characterised by limited treatment efficacy. The microbiota–gut–brain (MGB) axis has emerged as a potential therapeutic target for depression.
Hanchen Hou +15 more
wiley +1 more source
Correction to "Brain alpha-amylase: A novel energy regulator important in Alzheimer disease?" [PDF]
europepmc +1 more source
Associations Between Salivary Cortisol, DHEA-S, and Alpha-Amylase and Longitudinal Sleep Disruption in Shift-Working Healthcare Professionals: A Pilot Study. [PDF]
Salahuddin MF +6 more
europepmc +1 more source
Disrupted endocannabinoid signaling contributes to systemic inflammation in acute pancreatitis
Abstract Acute pancreatitis (AP) is an inflammatory disease that can lead to systemic complications in severe cases. The endocannabinoid system has emerged as a potential modulator of inflammation in AP. We investigated the role of the endocannabinoid 2‐arachidonoylglycerol (2‐AG) and the cannabinoid receptors CB1 and CB2 during AP.
Paula Goncalves‐Romeu +7 more
wiley +1 more source
Self-nanoemulsifying drug delivery system (SNEDDS) enhances the antidiabetic potential of <i>Averrhoa bilimbi</i> L. leaf extract: Integrated LC-MS/MS metabolomics, network pharmacology, and alpha-amylase inhibition. [PDF]
Aryani R +4 more
europepmc +1 more source
Differentiation of Novel Human .ALPHA.-Amylase from Salivary and Pancreatic .ALPHA.-Amylases.
OMICHI, Kaoru +3 more
openaire +2 more sources
ABSTRACT Aims There is an unmet need for effective pharmacotherapy for obesity disease management in Japan. Survodutide is a novel glucagon receptor/glucagon‐like peptide‐1 receptor (GLP‐1R) dual agonist with the potential to induce greater weight reductions than GLP‐1R mono‐agonists. We report the design and baseline participant characteristics of the
Koutaro Yokote +10 more
wiley +1 more source
ABSTRACT Aims Similar to blood, saliva contains a broad range of biomarkers and may offer a non‐invasive, repeatable specimen for endocrine and metabolic assessment. This review aims to synthesise and evaluate recent advances in the clinical translation of salivary biomarkers, while providing a critical assessment of the diagnostic reliability and ...
Chuyan Yu +7 more
wiley +1 more source

