Results 61 to 70 of about 49,741 (289)
Advanced Intelligent Systems, EarlyView.Researchers develop clinlabomics assisted for cancer identification, an artificial intelligence‐powered system using routine clinical lab data to detect and identify 10 cancer types. Tested on 19 199 individuals, it achieves 90.39% sensitivity and 82.41% specificity in cancer detection, with 72.57% accuracy in identifying specific cancer types ...
Bowen Zhang +9 more
wiley +1 more source
Serum αFP Level in Cord Blood of Full Term Neonates Born in Babol City
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2019 BACKGROUNDANDOBJECTIVE: Serum alpha-fetoprotein (αFP) level is considered as a diagnostic marker is higher than normal in many congenital tumors such as germ cell, hepatoblastoma, as well as liver and metabolic diseases in neonates.
Y Zahedpasha +3 more
doaj
Alpha-Fetoprotein and Hepatocellular Carcinoma Immunity
Canadian Journal of Gastroenterology and Hepatology, 2018 Hepatocarcinoma is one of the most prevalent gastroenterological cancers in the world with less effective therapy. As an oncofetal antigen and diagnostic marker for liver cancer, alpha-fetoprotein (AFP) possesses a variety of biological functions. Except
Xiaoping Wang, Qiaoxia Wang
doaj +1 more source
Epilepsia Open, EarlyView.Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira +5 more
wiley +1 more source
Targeting NAT10 Inhibits Hepatocarcinogenesis via ac4C‐Mediated SMAD3 mRNA Stability
Exploration, EarlyView.This study demonstrates that elevated N‐acetyltransferase 10 (NAT10) expression stabilizes SMAD3 mRNA through ac4C modification, promoting the progression of hepatocellular carcinoma (HCC). NAT10 also activates the TGF‐β signaling pathway, facilitating epithelial‐to‐mesenchymal transition and inhibiting anoikis. Furthermore, the authors develop a small‐
Yigan Zhang +16 more
wiley +1 more source
Binding characterization of the targeting drug AIMPILA to AFP receptors in human tumor xenografts
Tumor Biology, 2017 The main objective of this study was the characterization of preclinical tumor models based on their expression of alpha-fetoprotein receptor (RECAF) for targeting cancer cells with a new non-covalent complex (AIMPILA) containing alpha-fetoprotein as the
Janneta Tcherkassova +5 more
doaj +1 more source
Magnifying Glass on Sinonasal NUT Carcinoma Heterogeneity via Spatial Transcriptomics
Head &Neck, EarlyView.ABSTRACT Background Nuclear protein in testis (NUT) carcinomas (NCs) are rare, clinically aggressive tumors with characteristic translocation involving NUTM1 and BRD4 genes. While NCs are generally characterized by undifferentiated basaloid cells with focal/abrupt squamous differentiation, tumoral heterogeneity remains unexplored.
Diana Bell +8 more
wiley +1 more source
Immunoelectrophoretic quantitation of alpha-fetoprotein.
Clinical Chemistry, 1977 Abstract We describe an immunoelectrophoretic method for alpha-fetoprotein quantitation. The sensitivity of the method, which is easy to perform in the routine laboratory, is under the best conditions 50 mug/liter, but 83 mug/liter can always be detected.
M Pietrogrande +3 more
openaire +3 more sources
SVU - International Journal of Medical SciencesBackground:Viral hepatitis C represents a significant liver pathology worldwide, with a detrimental impact on national health systems. Objectives:The present study aimed to correlate the levels of serum α‑fetoprotein (AFP) with prognostic tools such as ...
Mohey Eldin Hassan Shikhoun* +1 more
doaj +1 more source