Results 21 to 30 of about 10,488 (304)

The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression

Hepatology, EarlyView., 2022
Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro, Rut Espinosa‐Sotelo, Eva Crosas‐Molist, Macarena Herranz‐Itúrbide, Daniel Caballero‐Díaz, Ania Alay, Xavier Solé, Emilio Ramos, Teresa Serrano, María L. Martínez‐Chantar, Ulla G. Knaus, José M. Cuezva, Antonio Zorzano, Esther Bertran, Isabel Fabregat   +14 more
wiley   +1 more source

Proteomic Analysis of Fetal Ovary Reveals That Ovarian Developmental Potential Is Greater in Meishan Pigs than in Yorkshire Pigs. [PDF]

PLoS ONE, 2015
Time-dependent expression of functional proteins in fetal ovaries is important to understand the developmental process of the ovary. This study was carried out to enhance our understanding of the developmental process of porcine fetal ovaries and to ...
Mengmeng Xu, Long Che, Dingyue Wang, Zhenguo Yang, Pan Zhang, Yan Lin, Zhengfeng Fang, Lianqiang Che, Jian Li, Daiwen Chen, De Wu, Shengyu Xu   +11 more
doaj   +1 more source

Pregnancy outcomes of women with elevated second-trimester maternal serum alpha-fetoprotein

Taiwanese Journal of Obstetrics & Gynecology, 2020
Objective: The aim of this study was to investigate the overall distribution of pregnancy outcomes in women with elevated second-trimester maternal serum alpha-fetoprotein (MS-AFP), and to determine the risk of adverse pregnancy outcomes (APOs) by MS-AFP
Ji-Lin Hu, Yang-Jia Zhang, Jin-Man Zhang, Shu Zhu, Dong-Mei Li, Yi-Fei Yin, Jie Su, Ying Chan, Jing He, Yong-Jiu Cao, Bao-Sheng Zhu   +10 more
doaj   +1 more source

A Rare Case of Lymph Node Metastasis from Early Gastric Cancer [PDF]

Clinical Endoscopy, 2019
Gastric cancers that fulfill the Japanese criteria for curative endoscopic resection show a low risk of lymph node (LN) metastasis. Here, we report a case of LN metastasis from early gastric cancer that fulfilled the curative criteria.
Takaaki Yoshikawa, Yoshio Kadokawa, Masaya Ohana, Akihisa Fukuda, Hiroshi Seno   +4 more
doaj   +1 more source

Usefulness of Highly Sensitive AFP-L3 and DCP in Surveillance for Hepatocellular Carcinoma in Patients with a Normal Alpha-Fetoprotein [PDF]

, 2014
Background and aims: Early detection of Hepatocellular Carcinoma (HCC) is crucial for effective management. Incidence of HCC has increased in the United States largely attributed to hepatitis B and C virus.
Coben, Robert, DiMarino, Anthony J., Hann, Hie-Won, Li, Dave, Satomura, Shinji, Yamada, Hiroyuki   +5 more
core   +2 more sources

An Unusual Case of Primary Retroperitoneal Germ Cell Tumour in a Young Man

European Journal of Case Reports in Internal Medicine, 2018
Some 2–5% of germ cell tumours are of extragonadal origin, with a retroperitoneal location being very rare. The majority of retroperitoneal germ cell tumours have metastasized from a testicular tumour.
Maria João Raposo Linhares Serpa, Susana Franco, Diana Repolho, Francisco Branco, João Gramaça, José Ferreira Júnior   +5 more
doaj   +1 more source

Aszites, Pfortaderthrombose und hepatische Enzephalopathie bei Leberzirrhose: Aktuelle Therapieempfehlungen [PDF]

, 2012
Treatment of Ascites, Portal Vein Thrombosis and Hepatic Encephalopathy in Patients with Cirrhosis of the Liver Background: Ascites, portal vein thrombosis and hepatic encephalopathy are important complications of cirrhosis of the liver.
Abecasis R, Acosta S, Alexander L. Gerbes, Als-Nielsen B, Als-Nielsen B, Amitrano L, Amitrano L, Amitrano L, Arroyo V, Bajaj JS, Bellot B, Bismuth M, Córdoba J, D'Avola D, de Franchis V, DeLeve LD, Fiaccadori F, Francoz C, Francoz C, Gerbes AL, Gerbes AL, Gerbes AL, Gines P, Gluud LL, Gülberg V, Han G, Häussinger D, Luca A, Montagnese S, Prasad S, Rajani R, Rivkin A, Rosemurgy AS, Rossle M, Rössle M, Salerno F, Salerno F, Salerno F, Sanyal AJ, Senzolo M, Tarantino G, Tublin ME, Veit Gülberg, Wong F, Wong F, Zillikens MC, Zocco MA   +46 more
core   +1 more source

Prognostic Model for Hepatocellular Carcinoma with Time-Dependent Factors [PDF]

, 2011
The purpose of this study was to build a prognostic model of hepatocellular carcinoma (HCC) using time-dependent covariates to re-evaluate the prognosis at any stage of the disease.
Hagihara, Hiroaki, Ito, Yoichi M., Iwadou, Shouta, Iwasaki, Yoshiaki, Kobashi, Haruhiko, Kobayashi, Yoshiyuki, Kuwaki, Kenji, Miyake, Yasuhiro, Miyatake, Hirokazu, Miyoshi, Kenji, Nakamura, Shinichiro, Nouso, Kazuhiro, Onishi, Hideki, Shiraha, Hidenori, Shoji, Bon, Takaki, Akinobu, Toshimori, Junichi, Yamamoto, Kazuhide, Yasunaka, Tetsuya   +18 more
core   +1 more source

A systematic review of progress on hepatocellular carcinoma research over the past 30 years: a machine-learning-based bibliometric analysis [PDF]

, 2023
IntroductionResearch on hepatocellular carcinoma (HCC) has grown significantly, and researchers cannot access the vast amount of literature. This study aimed to explore the research progress in studying HCC over the past 30 years using a machine learning-
Hee Ju Sohn, Ji Woong Hwang, Kiseong Lee, Sanggyun Suh, Sun-Whe Kim   +4 more
core   +1 more source

Pre-treatment alphafeto protein in hepatocellular carcinoma with non-viral aetiology – a prospective study

BMC Gastroenterology, 2017
Background Alpha-fetoprotein (AFP) is a biomarker for hepatocellular carcinoma (HCC). The significance of pre-treatment AFP (pt-AFP) in non-viral HCC (nvHCC) is not clear.
Siriwardana Rohan Chaminda, Thilakarathne Suchintha, Niriella Madunil Anuk, Dassanayake Anuradha Supun, Gunathilake Mahen Bhagya, Liyanage Chandika Anuruddha Habarakada, De Silva Hithadurage Janaka   +6 more
doaj   +1 more source