Results 251 to 260 of about 286,880 (314)

Hesperidin and raffinose dietary supplementation enhances immune responses, antioxidant‐related gene expression, hematological parameters, and growth performance in juvenile common carp (Cyprinus carpio)

open access: yesJournal of the World Aquaculture Society, Volume 57, Issue 2, April 2026.
Abstract This study evaluated the individual and combined effects of two dietary immunomodulators, raffinose and hesperidin, on multiple physiological parameters in common carp (Cyprinus carpio), including growth performance, feed efficiency, hematological indices, serum immunological markers, and the expression of genes related to antioxidant capacity.
Ali Arshadi   +3 more
wiley   +1 more source

Rhizobial motility preference in root colonization of Medicago truncatula

open access: yesNew Phytologist, Volume 250, Issue 1, Page 547-562, April 2026.
Summary Tunnel‐like infection thread (IT) structures support root colonization by symbiotic nitrogen‐fixing rhizobia bacteria in most legume species. These tip‐grown structures are key to directing rhizobia from root hairs to developing nodules, where they are hosted to fix nitrogen.
Anaïs Delers   +11 more
wiley   +1 more source

Detection of Mesenchymal Stem Cell Aging Using an Integrin Mechano‐Probe

open access: yesAnnals of the New York Academy of Sciences, Volume 1558, Issue 1, April 2026.
ABSTRACT Mesenchymal stem cells (MSCs) play a crucial role in cell therapy, but their efficacy diminishes with age. While biochemical methods like flow cytometry, immunoblotting, β‐galactosidase labeling, and gene profiling are effective for screening MSC aging, mechanical factors also change with aging.
Aimei Liu   +10 more
wiley   +1 more source

Robust immune cell infiltration and macrophage senescence occur within a week of recovery after limb immobilization in older adult skeletal muscle

open access: yesThe Journal of Physiology, Volume 604, Issue 8, Page 3379-3395, 15 April 2026.
Abstract figure legend During the 7 days of muscle recovery following 14 days of unilateral limb immobilization, older adults (compared to young) exhibited a robust immune cell infiltration, characterized largely by CD68+ CD206+ macrophages. This response coincided with an expansion of senescent macrophages and was associated with excessive collagen ...
Chad M. Skiles   +9 more
wiley   +1 more source

ZNF384‐Driven Fibulin‐1 Exacerbates Vascular Stiffness via TGF‐β/Smad3‐Mediated Senescence and Fibrosis

open access: yesThe FASEB Journal, Volume 40, Issue 6, 31 March 2026.
This article elucidates the regulatory molecular mechanisms of Fibulin‐1 (Fbln1) in vascular stiffness and explores potential therapeutic interventions. Zinc Finger Protein 384 (ZNF384) binds to the Fbln1 promoter, driving its expression. Fbln1 activates the TGF‐β/Smad3 axis, promoting vascular smooth muscle cell (VSMC) senescence and collagen ...
Dan Yan   +11 more
wiley   +1 more source

UGA4 and YBR062C Regulate Oxidative Stress Tolerance Under Heavy Metal Toxicity

open access: yesThe FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Under heavy metal stress, global cap‐dependent translation is compromised. However, expression of URE2, a key gene involved in cellular tolerance to heavy metal toxicity, is maintained through an internal ribosome entry site (IRES)–mediated mode of translation.
Mustafa Al‐gafari   +8 more
wiley   +1 more source

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