Results 141 to 150 of about 8,293 (202)

Age-dependence of alpha-MSH-induced anorexia

Neuropeptides, 2010
Long-term regulation of energy balance involves two major trends: first age-related obesity develops in the middle-aged, later it is followed by anorexia of aging (sarcopenia and/or cachexia). A dynamic balance between orexigenic and anorexigenic neuropeptides is essential for the regulation of energy homeostasis.
E Petervari, M Székely
exaly   +3 more sources

Ingested (oral) alpha-MSH inhibits acute EAE

Journal of Neuroimmunology, 2008
Ingested type I IFN and SIRS peptide administered orally inhibit EAE. We examined whether another immunoactive protein, tridecapeptide alpha-MSH, would have similar anti-inflammatory effects in EAE after oral administration. B6 mice were immunized with MOG peptide 35-55 and gavaged with 0.1 ml of control saline or alpha-MSH peptide starting on day -7 ...
Staley Brod
exaly   +3 more sources

Alpha-MSH peptides inhibit acute inflammation and contact sensitivity

Peptides, 1990
Alpha-melanocyte stimulating hormone [alpha-MSH(1-13)] occurs within the CNS, skin, circulation and in other body sites. This tridecapeptide and its COOH-terminal tripeptide, alpha-MSH (11-13), have antipyretic and anti-inflammatory actions. Studies of the anti-inflammatory effects of these molecules have been confined mainly to tests of inhibition of ...
James M Lipton, J M Lipton
exaly   +3 more sources

Acute phase response to endotoxin: rise in plasma alpha-MSH and effects of alpha-MSH injection

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 1990
Endotoxins, cell wall components of bacteria, cause a number of biological effects, presumably via induction of potent cytokines. Previous research suggests that the neuropeptide alpha-melanocyte-stimulating hormone (alpha-MSH) and its COOH-terminal tripeptide reduce the effects of cytokines.
L W, Martin, J M, Lipton
openaire   +2 more sources

ALPHA-MSH STIMULATION OF GROWTH HORMONE RELEASE

The Journal of Clinical Endocrinology & Metabolism, 1973
The tridecapeptide 1–13 of human ACTH (∞-MSH) was found to induce GH release in 18 among 23 normal males ; peak values occurred at 30 or 45 min. ∞-MSH was given IV over 1 min at a dose of 0.5 mg. No change in blood cortisol or glucose were found while minimal side effects occurred in only 4 subjects. GH did not rise after placebo injection.
G, Strauch, D, Girault, M, Rifaĭ, H, Bricaire   +3 more
openaire   +2 more sources

Des-acetyl-alpha-MSH and not alpha-MSH is the major form of alpha-MSH in amniotic fluid.

Journal of endocrinological investigation, 1988
Immunoreactive alpha-melanocyte stimulating hormone (IR-alpha-MSH)-like activity was measured by radioimmunoassay (RIA) in at term pregnancy amniotic fluid prior and after adsorption on a Sep-pak C18 cartridge. alpha-MSH activity was 3-4 times lower after Sep-pak purification but, unlike the levels of IR-alpha-MSH in the fluid analyzed in toto ...
A, Mauri, A, Argiolas, M R, Melis, L, Lai, W, Fratta, A, Caruso, A, Lanzone, F, Serri, F, Caminiti, S, Mancuso   +9 more
openaire   +1 more source

alpha-MSH and desacetyl-alpha-MSH signaling through melanocortin receptors.

Annals of the New York Academy of Sciences, 2003
The functional significance of N-terminal acetylation of ACTH[1-13]NH(2) is unknown. N-terminal acetylation of ACTH[1-13]NH(2) (known as desacetyl-alpha-MSH) to produce alpha-MSH enhances some activities of ACTH[1-13]NH(2) and virtually eliminates others.
Kathleen G, Mountjoy, Chia-Shan Jenny, Wu, Jillian, Cornish, Karen E, Callon   +3 more
openaire   +1 more source

[Alpha-MSH and pregnancy].

Zeitschrift fur Hautkrankheiten, 1989
In 32 pregnant women, we repeatedly determined the levels of alpha-MSH, melatonin, ACTH and progesterone. In the radioimmunoassay, all of these hormones showed a significant increase from the first to the third trimester. In contrast to progesterone, neither the level of alpha-MSH nor that of melatonin rises significantly until between the 28th and ...
P, Altmeyer, A, Bernd, H, Holzmann, M, Bacharach-Buhles, E, Halberstadt   +4 more
openaire   +1 more source