A peptide display system identifies a potent mutant β-melanocyte-stimulating hormone agonist of melanocortin-4 receptor. [PDF]
Lin A +7 more
europepmc +1 more source
Physical exercise increases binding of POMC to blood extracellular vesicles. [PDF]
Santos MF +13 more
europepmc +1 more source
Biological Roles of Melanin and Natural Product-Derived Approaches for Its Modulation. [PDF]
Hong S, Lim H, Kim DH.
europepmc +1 more source
Breed difference in the regulation of feather coloration in chickens [PDF]
Nishio, Kaori +4 more
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Comparative Efficacy of Skin-Lightening Formulations in Suppressing Ultraviolet B (UVB)-Induced Arachidonic Acid, Alpha-Melanocyte-Stimulating Hormone (α-MSH), and Melanin Expression: An In Vitro Keratinocyte-Melanocyte Co-culture Study. [PDF]
Ribero S +3 more
europepmc +1 more source
Natural dual inhibitor isorhamnetin-3-O-neohespeidoside targets tyrosinase and MC1R for skin pigmentation management. [PDF]
Deng R +5 more
europepmc +1 more source
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Age-dependence of alpha-MSH-induced anorexia
Neuropeptides, 2010Long-term regulation of energy balance involves two major trends: first age-related obesity develops in the middle-aged, later it is followed by anorexia of aging (sarcopenia and/or cachexia). A dynamic balance between orexigenic and anorexigenic neuropeptides is essential for the regulation of energy homeostasis.
E, Pétervári +4 more
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Ingested (oral) alpha-MSH inhibits acute EAE
Journal of Neuroimmunology, 2008Ingested type I IFN and SIRS peptide administered orally inhibit EAE. We examined whether another immunoactive protein, tridecapeptide alpha-MSH, would have similar anti-inflammatory effects in EAE after oral administration. B6 mice were immunized with MOG peptide 35-55 and gavaged with 0.1 ml of control saline or alpha-MSH peptide starting on day -7 ...
Staley A, Brod, Zachary M, Hood
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ALPHA-MSH STIMULATION OF GROWTH HORMONE RELEASE
The Journal of Clinical Endocrinology & Metabolism, 1973The tridecapeptide 1–13 of human ACTH (∞-MSH) was found to induce GH release in 18 among 23 normal males ; peak values occurred at 30 or 45 min. ∞-MSH was given IV over 1 min at a dose of 0.5 mg. No change in blood cortisol or glucose were found while minimal side effects occurred in only 4 subjects. GH did not rise after placebo injection.
G, Strauch +3 more
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Acute phase response to endotoxin: rise in plasma alpha-MSH and effects of alpha-MSH injection
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 1990Endotoxins, cell wall components of bacteria, cause a number of biological effects, presumably via induction of potent cytokines. Previous research suggests that the neuropeptide alpha-melanocyte-stimulating hormone (alpha-MSH) and its COOH-terminal tripeptide reduce the effects of cytokines.
L W, Martin, J M, Lipton
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