Results 51 to 60 of about 10,436 (217)

Prolylcarboxypeptidase (PRCP) as a new target for obesity treatment

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2010
B Shariat-Madar1, D Kolte2, A Verlangieri2, Z Shariat-Madar21College of Literature, Science, and the Arts, University of Michigan, Ann Arbor MI, USA; 2School of Pharmacy, Department of Pharmacology, University of Mississippi, University, MS, USAAbstract:
Shariat-Madar Z   +4 more
doaj   +2 more sources

The action of CGRP and SP on cultured skin fibroblasts [PDF]

open access: yes, 2014
Calcitonin gene-related peptide (CGRP) is the most abundant neuropeptide in the skin, followed by substance P (SP), vasoactive intestinal peptide (VIP), and other neuropeptides in smaller amounts.
Ferreira, Lydia Masako   +5 more
core   +1 more source

Ultra‐Fast and Economical Pre‐Breakdown Electrochemical Synthesis of Intrinsically Conductive Polymer Suspension for Production of Safe Lithium‐Ion Batteries

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This paper presents a breakthrough pre‐breakdown electrochemical method for synthesizing polyNiMeOSalen suspensions, achieving an 83% yield and nanoscale dispersion ($1500/kg) and environmental impact (1.42 kg CO2eq/kg). We report a novel pre‐breakdown electrochemical synthesis method for producing polyNiMeOSalen suspensions with exceptional ...
Evgenii Beletskii   +6 more
wiley   +1 more source

Protective effects of Met-enkephalin on alcohol induced gastric lesions [PDF]

open access: yes, 2000
The model of ethanol induced gastric lesions is useful in the evaluation of gastric cytoprotection. We used it to measure cytoprotective effects of two neuropeptides, Met-enkephalin (Peptid-M, LUPEX(R)) and alpha -melanocyte stimulating hormone (alpha ...
Alenka Boban-Blagaić   +8 more
core   +1 more source

Hierarchical modeling of melanocortin 1 receptor variants with skin cancer risk [PDF]

open access: yes, 2018
The human MC1R gene is highly polymorphic among lightly pigmented populations, and several variants in the MC1R gene have been associated with increased risk of both melanoma and nonmelanoma skin cancers. The functional consequences of MC1R gene variants
Han, Jiali   +3 more
core   +1 more source

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

open access: yesEpilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira   +5 more
wiley   +1 more source

Beneficial Effect of Covalently Grafted α-MSH on Endothelial Release of Inflammatory Mediators for Applications in Implantable Devices.

open access: yesPLoS ONE, 2016
Intravascular devices for continuous glucose monitoring are promising tools for the follow up and treatment of diabetic patients. Limiting the inflammatory response to the implanted devices in order to achieve better biocompatibility is a critical ...
Guillaume Le Saux   +5 more
doaj   +1 more source

Dimethyl Itaconate Reduces α-MSH-Induced Pigmentation via Modulation of AKT and p38 MAPK Signaling Pathways in B16F10 Mouse Melanoma Cells

open access: yesMolecules, 2022
Dimethyl itaconate (DMI) exhibits an anti-inflammatory effect. Activation of nuclear factor erythroid 2-related factor 2 (NRF2) is implicated in the inhibition of melanogenesis.
Sungchan Jang   +2 more
doaj   +1 more source

Expanding the genotypic spectrum of PCSK1 deficiency: A novel mutation in severe neonatal diarrhea

open access: yesJPGN Reports, EarlyView.
Abstract Among congenital diarrhea and enteropathies (CODEs), proprotein convertase subtilisin/kexin type 1 (PCSK1) deficiency is a rare monogenic disorder, associated with severe neonatal diarrhea and polyendocrinopathies. We report an 18‐day‐old male neonate, born to consanguineous parents, presenting with persistent watery diarrhea, metabolic ...
Eleonora Saraceno   +7 more
wiley   +1 more source

Inhibition of Melanogenesis via Passive Immune Targeted Alpha-MSH Binder Polypeptide

open access: yesCosmetics
Alpha-melanocyte stimulating hormone (α-MSH) is a hormone that stimulates the formation of melanin, which is responsible for protecting the skin from UV rays.
Se-Hyo Jeong   +8 more
doaj   +1 more source

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